沈阳及北京地区儿童青少年手腕骨骨龄评价  

Evaluation of bone age of wrist-hand in adolescent of Shenyang and Beijing

作　　者：赵旭东[1] 胡奕[1] 潘诗农[1] 李晓飞[1] 李新民[2] 程晓光[2] 郭启勇[1] 

机构地区：[1] 中国医科大学附属盛京医院放射科,沈阳110004 [2]北京大学第四临床医学院北京积水潭医院放射科

出　　处：《中华放射学杂志》2013年第12期1066-1069,共4页Chinese Journal of Radiology

基　　金：盛京自由研究者基金资助项目（201208）

摘　　要：目的 评价沈阳、北京两地青少年手腕骨骨龄实际状况.方法 选取沈阳、北京两地1333例4.0～18.0岁正常青少年左手腕部X线片,依据CHN骨龄标准图谱评价手腕骨骨龄.采用Pearson相关性分析评估骨龄和生活年龄的相关性;采用配对t检验评估骨龄和生活年龄的差异;采用独立样本t检验比较骨龄和生活年龄的差值,分别评价两地区及两性别间的差异.P ＜0.05表示差异有统计学意义.结果 （1）沈阳、北京两地青少年骨龄与生活年龄明显相关（沈阳男、女性r值分别为0.958、0.951,北京男、女性r值分别为0.942、0.953,P值均＜0.01）.（2）骨龄和生活年龄的比较,16个年龄组骨龄高于生活年龄,差异有统计学意义,包括沈阳男性6.0 ～18.0岁阶段6个年龄组、沈阳女性6.0～7.9岁和14.0～15.9岁2个年龄组、北京男性6.0～15.9岁阶段5个年龄组和北京女性8.0～13.9岁阶段3个年龄组.（3）两性别间骨龄与生活年龄差值比较,沈阳地区8.0 ～9.9岁、10.0 ～11.9岁和16.0 ～ 18.0岁3个年龄组差异有统计学意义,北京地区6.0 ～7.9岁和10.0 ～11.9岁2个年龄组差异有统计学意义.（4）两地区间骨龄与生活年龄差值比较,男性青少年10.0 ～11.9岁、12.0 ～ 13.9岁及16.0 ～ 18.0岁3个年龄组差异有统计学意义,女性青少年6.0 ～7.9岁、8.0 ～9.9岁和10.0～ 11.9岁3个年龄组差异有统计学意义.结论 CHN骨龄标准图谱可反映青少年骨龄发育进程;两地青少年多个年龄组骨龄高于生活年龄;两地区及两性别间骨龄与生活年龄的差值在部分年龄段存在差异.本结果可为研究骨龄地域和性别差异及进一步修订青少年骨龄评价标准提供依据.Objective To investigate bone age of left-hand wrist in healthy adolescents of Shenyang and Beijing for assessing the process of skeletal development.Methods From 2008 to 2012,1333 adolescents （aged form 4.0 to 18.0 ys） of Shenyang and Beijing were enrolled in this study.Skeletal age was estimated by left hand and wrist X-ray using CHN atlas by 2 qualified radiologists.The correlation between skeletal and chronological age was analyzed using correlation analysis.Skeletal age and chronological age were compared using paired t test.The differences between skeletal and chronological age in genders and regions were compared using independent-samples t test.SPSS for Windows （version 13.0）was used for statistical analysis.P 〈 0.05 was considered as significant difference.Results （1） Close correlation was found between skeletal age and chronological age （P 〈 0.01） for both two genders and two regions.（2）Among 28 groups of investigation,16 groups （boys,11 groups） had higher skeletal ages than chronological ages with statistical significance,including Shenyang boys aged 6.0-18.0 ys,Shenyang girls aged 6.0-7.9 ys and 14.0-15.9 ys,Beijing boys at 6.0-15.9 ys and Beijing girls at 8.0-13.9 ys.（3） Comparison between boys and girls：5 groups showed significant difference,including 8.0-9.9 ys,10.0-11.9 ys and 16.0-18.0 ys groups in Shenyang and 6.0-7.9 ys,10.0-11.9 ys groups in Beijing.（4） Comparison between Shenyang and Beijing：6 groups showed statistical significance,including boys at 10.0-11.9 ys,12.0-13.9 ys and 16.0-17.9 ys and girls at 6.0-7.9 ys,8.0-9.9 ys and 10.0-11.9 ys.Conclusion Although CHN atlas method could reflect adolescent bone development,the skeletal age is higher than chronological age in many groups,and the difference between skeletal and chronological age is statistically different between genders and between two regions.This research can be used as a reference for the study of skeletal development and for further emendation of CHN atlas.

关 键 词：年龄测定 骨骼 放射摄影术 儿童 青少年 

分 类 号：R816.8[医药卫生—放射医学]