感染可能性评分对血液系统肿瘤患者血流感染的预测作用  

Application of infection probability score in assessment on bloodstream infection in patients with haematological malignancy

作　　者：梅俊辉[1] 

机构地区：[1]中国人民解放军总医院血液病科,北京100853

出　　处：《海南医学》2013年第23期3539-3541,共3页Hainan Medical Journal

摘　　要：目的探讨感染可能性评分(IPS)预测血液系统肿瘤患者发生血流感染(BSI)的可行性。方法选取血液恶性肿瘤患者90例,所有患者在化疗前进行一次IPS评分,并且自进入病房至出院或死亡均监测有无BSI的发生,利用工作特征曲线评价IPS诊断BSI的价值。结果所有患者IPS评分平均为(11.80±6.54)分,BSI的发生率为11.11%;其中未发生BSI患者IPS评分为(10.62±5.90)分,明显低于发生BSI患者的IPS评分[(13.85±7.10)分],两者比较差异有统计学意义(t=1.853,P=0.040)。IPS评分系统预测BSI最佳值为13.0,灵敏度为79.75%,特异度为76.89%,曲线下面积为0.72,阳性预测值为65.83%,阴性预测值为91.33%。结论 IPS可作为一个筛选BSI的有价值的工具,对于开展预见性护理、提高护理质量具有重要意义。Objective To investigate the predictive power of infection probability score （IPS） for blood- stream infection （BSI） in patients with haematological malignancy. Methods Ninety patients with haematological malignancy were included in the study. All the subjects were assessed using IPS before chemotherapy and were moni- tored for BSI from the admission until the discharge from the unit or death. ROC curve was used to assess the predic- tive power of IPS for BSI. Results The mean score of the participants was （11.80＋6.54）. The incidence rate of BSI was 11.11%. Compared with the patients without BSI, the score of patients with BSI was significantly higher [（13.85~ 7.10） vs （10.62~5.90）, t=1.853, P=0.040]. The best cutoff value oflPS for the prediction of BSI was 13, with a sensi- tivity of 79.75%, a specificity of 76.89%, AUC of 0.72, a positive predictive value of 65.83% and a negative predic- tive value of 91.33%. Conclusion IPS is regarded as a valued screen for BSI in patients with haematologieal malig- nancy. It is important to carry out predictive nursing and improve nursing quality.

关 键 词：感染可能性评分 血液系统肿瘤 血流感染 

分 类 号：R733[医药卫生—肿瘤]