BISAP、Ranson’s、APACHEⅡ和CTSI评分系统在急性胰腺炎评估中的价值  被引量:41

Comparison of BISAP, Ranson' s, APACHE II and CTSI scores in evaluating the severity of acute pancreatitis

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作  者:邹金艳[1] 林军[1] 易三凤[1] 向琴[1] 商建[1] 夏冰[1] 邓长生[1] 

机构地区:[1]430071,武汉大学中南医院消化内科 武汉大学医学院消化系统疾病研究中心

出  处:《中华消化外科杂志》2014年第1期39-43,共5页Chinese Journal of Digestive Surgery

摘  要:目的探讨急性胰腺炎床旁指数(BISAP)、Ranson’s、APACHEⅡ、CT严重程度指数(CTSI)4种评分系统在急性胰腺炎患者严重程度评估中的价值。方法回顾性分析2005年至2011年武汉大学中南医院收治的385例急性胰腺炎患者的临床资料,探讨BISAP、Ranson’s、APACHEⅡ、CTSI4种评分系统在急性胰腺炎严重程度评估中的价值。采用,检验和受试者工作曲线(ROC)评估4种评分系统预测患者发生重症急性胰腺炎、局部并发症和死亡的价值,并计算优势比(OR),用Z检验比较曲线下面积(AUC)的差异。结果BISAP评分≥3分者的重症急性胰腺炎发生率、局部并发症发生率、病死率分别为64.4%(56/87)、16.1%(14/87)、8.0%(7/87),高于BISAP评分≤2分者的13.4%(40/298)、6.4%(19/298)、0.3%(1/298),两者比较,差异有统计学意义(X2=93.4,8.1,19.7,P〈0.05)。Ranson’s评分≥3分者的重症急性胰腺炎发生率、局部并发症发生率、病死率分别为52.7%(48/91)、22.0%(20/91)、7.7%(7/91),高于ltanson’s评分≤2分者的16.3%(48/294)、4.4%(13/294)、0.3%(1/294),两者比较,差异有统计学意义(X^2=49.2,27.3,18.5,P〈0.05)。APACHEII评分≥8分者的重症急性胰腺炎发生率、局部并发症发生率、病死率分别为46.6%(27/58)、20.7%(12/58)、8.6%(5/58),高于APACHEⅡ评分≤7分者的21.1%(69/327)、6.4%(21/327)、0.9%(3/327),两者比较,差异有统计学意义(X^=17.0,12.8,14.4,P〈0.05)。CTSI评分≥4分者的重症急性胰腺炎发生率、局部并发症发生率、病死率均分别为51.4%(19/37)、51.4%(19/37)、16.2%(6/37),高于CTSI评分≤3分者的22.2%(77/347)、4.0%(14/347)、0.6%(2/347),�Objective To investigate the value of the bedside index for severity in acute pancreatitis (BISAP), Ranson's, APACHE II and computed tomography severity index (CTSI) scoring system in evaluating the severity of acute pancreatitis. Methods The clinical data of 385 patients with acute pancreatitis who were admitted to the Zhongnan Hospital of Wuhan University from 2005 to 2011 were retrospectively analyzed. The values of 4 scoring systems including BISAP, Ranson's, APACHE Ⅱ and CTSI in predicting the incidences of severe acute pancreatitis, local complications and death were investigated by Chi-square test and receiver operating characteristic curve. Odds ratio (OR) was calculated. The differences of areas under the curves (AUC) were analyzed using the Z test. Results The incidences of severe acute pancreatitis, local complications and mortality of patients with BISAP score I〉 3 were 64.4% (56/87), 16. 1% (14/87) and 8.0% (7/87), which were significantly higher than 13.4% (40/298), 6.4% ( 19/298 ) and 0.3 % ( 1/298 ) of patients with BISAP score 〈 2 (X2 = 93.4, 8.1, 19.7, P 〈 0.05 ). The incidences of severe acute pancreatitis, local complications and mortality of patients with Ranson's score ~ 3 were 52.7% (48/91), 22.0% (20/91) and 7.7% (7/91), which were significantly higher than 16.3% (48/294), 4.4% (13/294) and 0.3% (1/294) of patients with Ranson's score ~〈2 (Xz =49. 2, 27.3, 18.5, P 〈 0.05 ). The incidences of severe acute panereatitis, local complications and mortality of patients with APACHE ]1 score/〉 8 were 46.6% ( 27/58 ), 20.7% ( 12/58 ) and 8.6% ( 5/58 ), which were significantly higher than 21. 1% (69/327) , 6.4% (21/327) and O. 9% (3/327) of patients with APACHE U score~〈7 (XZ= 17.0, 12. 8, 14. 4, P〈0.05). The incidences of severe acute panereatitis, local complications and mortality of patients with CTSI score i〉4 were 51.4% (19/37), 51.4% (19/37), 16.2% (6/37)

关 键 词:急性胰腺炎 预后 BISAP Ranson’s APACHE  CTSI 

分 类 号:R576[医药卫生—消化系统]

 

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