GC法测定新型狗皮膏中樟脑的含量  

Determination of Camphor in New Goupi Adhesive Plaster by Capillary Gas Chromatography

作　　者：胡丹[1] 王静[2] 曹红[1] 邢俊波[1] 陈玉敏[1] 

机构地区：[1]总后勤部卫生部药品仪器检验所,北京100166 [2]南京军区福州总医院第二住院部医护办,福建福州350025

出　　处：《解放军药学学报》2013年第6期536-537,共2页Pharmaceutical Journal of Chinese People's Liberation Army

摘　　要：目的初步建立新型狗皮膏中樟脑的含量测定方法。方法 GC法采用弹性石英毛细管柱DB-WAX（柱长30 m,内径0.32 mm,膜厚度0.25μm）,FID检测器;柱温为110℃;结果樟脑含量计算的回归方程为Y=3229.2 X-15.657,r=0.9997,在0.033 88~1.694μg范围内,呈良好的线性关系,样品的平均回收率为96.90%,RSD为1.74%。结论本法重复性好,快速、简便,可作为该产品的质量控制方法。Objective To establish a method for determination of camphor in a new goupi adhesive plaster. Methods The GC system consisted of a DB-WAX capillary column（30. 0 m long,0. 25 μm thick,0. 32 mm wide） with nitrogen as the carrier gas. The column temperature was set at 110 ℃. Results The regression equation for camphor was Y = 3229. 2 X-15. 657,r = 0. 9997,and the linear range was 0. 033 88-1. 694 μg. The average recovery of camphor was 96. 90%（RSD = 1. 74%）. Conclusion This method is reproducible,simple and suitable for quality control of the preparation。

关 键 词：GC 樟脑 新型狗皮膏 

分 类 号：R927.2[医药卫生—药学]