眼球挫伤对角膜内皮细胞的影响  

The effects of ocular contusion on corneal endothelium

作　　者：刘丽[1] 王永恒[2] 任凤杰[1] 穆凤平[1] 

机构地区：[1]秦皇岛市第一医院眼科,066000 [2]秦皇岛市第一医院神经外科,066000

出　　处：《中华眼外伤职业眼病杂志》2013年第12期884-886,共3页Chinese Journal of Ocular Trauma and Occupational Eye Disease

摘　　要：目的探讨眼球挫伤对角膜内皮细胞形态的影响。方法应用非接触型角膜内皮显微镜对有眼球挫伤史者27例（54只眼）的伤眼（27只眼）及对侧健眼（27只眼）角膜内皮细胞进行观察，测量数据以SPSS16．0进行统计学分析。结果角膜内皮细胞密度眼球挫伤组为（1840．80±332．87）／mm2较健眼组的（2694．30±211．32）／mm2下降（t=9．729，P〈0．01）；平均细胞面积挫伤组为（568．16±147．61）μm。较健眼组的（359．33±69．07）μm2增大（t=6．463，P〈0．01）；平均细胞而积的标准差挫伤组为243．41±135．45较健眼组的161．12±19．00增大t=4．765，P〈0．01）；细胞面积的变异系数挫伤组为（41．10±10．17）％较健眼组的（31．01±3．53）％增大（f=4．915，P〈0．01）；六角形细胞所占比例挫伤组为（49．88±9．07）％较健眼组的（57．71±5．30）％降低（t=3．581，P〈0．01）。结论眼球挫伤可致角膜内皮细胞单位面积细胞密度F降、平均细胞面积增大、平均细胞面积的标准差增大、细胞面积的变异系数增加和六角形细胞所占比例下降。Objective To investigate the influence of ocular contusion on corneal endothelium. Methods Twenty - seven eyes of 27 cases of ocular contusion were enrolled in the study as the clinical trial group. The contralateral healthy eyes of all cases were regarded as the control group. The corneas was meas- ured by non - contact specular microscope. The data were analyzed by SPSS 16.0. A P value less than 0.05 was considered statistically significant. Results The corneal endothelial cell density （CD） in the experi- ）/mm was lower than the control group （2694.30 ± 211.32）/ram2 signifimental group （ 1840.80 ±332.87 2 eantly （t = 9. 729 ,P 〈 0.01 ）. The average cell area （ACA） in the experimental group （568.16 - 147.61 ）μm2 was larger than the control group （ 359.33± 69.07 ） wn2 significantly （ t = 6. 463, P 〈 0.01 ）. The standard deviation of average area in the trial group （243.41± 135.45 ） was bigger than the control group （ 161.12 ±19.00） significantly （t =4. 765 ,P 〈0.01 ）. The coeffieent of variation of cell size in the trial group （41.10 ± 10. 17 ） % was larger than the control group （ 31.01 ± 3.53 ） % significantly （ t = 4. 915, P 〈 0.01 ）. The percentage of hexagonal cells （6A） of the trial group （49.88±9.07 ） % was smaller than the eontrol group （ 57.71± 5.30） % significantly （ t = 3. 581, P 〈 0.01 ）. Conclusion Compared with the healthy eyes, corneas with ocular contusion has smaller CD and 6A, larger ACA, CV and standard deviation.

关 键 词：挫伤 眼球 内皮细胞 角膜 

分 类 号：R779.1[医药卫生—眼科]