1539例精神疾患的事件相关脑电位定性分析  

QUALITATIVE ANALYSIS OF EVENT- RELATED POTENTIALS IN 1539 PATIENTS WITH MENTAL DISORDERS

作　　者：殷光中[1] 李哲[1] 董日霞[1] 杨建功[1] 杨勇[1] 张广亚[1] 沈建红[1] 盖海军[1] 吴正言[1] 杜向东[1] 

机构地区：[1]苏州大学附属广济医院临床精神科,215008

出　　处：《现代电生理学杂志》2013年第4期198-201,共4页Journal of Modern Electrophysiology

基　　金：江苏省临床医学科技专项(BL2013018);苏州市科技计划项目(SYS201157;SYSD2011122);苏州市卫生局科教兴卫基金(KJXW2011032)

摘　　要：目的:分析事件相关电位在精神科疾病中的异常检出率及主要临床检查病种。方法:对1539例申请事件相关电位检查患者的P300、P50和CNV结果进行定性分析,分析其异常检出率并统计其检查病种。结果:本组精神疾患P300、P50、CNV的异常检出率分别为54.5%、61.5%和60.1%。临床申请作ERP检查的前三位病种分别是慢性精神分裂症偏执型、复发性抑郁症、首发精神分裂症(阴性症状为主)。结论:高密度脑电图及ERP新技术较适合精神科和心理学,值得进一步推广。Objective：To analyse the abnormal rate of event-related potentials（ERP）in mental disorders and the main diseases applied for ERP examination. Methods：Qualitative analysis of P300,P50 and CNV were used in 1539 patients with mental disorders who applied for ERP examination. Abnormal rate of ERP and the main diseases which applied for ERP were calculated. Results：The abnormal rate of P300,P50 and CNV in 1539 patients were 54.5%,61.5% and 60.1% respectively,and the top 3 disease were chronic paranoid schizophrenia,recurrent depression and first- episode schizophrenia with dominantly negative symptoms. Conclusion：High density electroencephalogram（EEG）and ERP are suitable technology for clinical examination in psychiatry and psychological department and are worth further popularized.

关 键 词：事件相关电位 P300 P50 关联性负变 精神疾病 临床推广 

分 类 号：R749[医药卫生—神经病学与精神病学]