68例前颅底脑膜瘤的显微外科治疗  

Microsurgical treatment for meningiomas at anterior skull base: experience of 68 cases

作　　者：陈景宇[1] 陈志[1] 胡荣[1] 孟辉[1] 林江凯[1] 朱刚[1] 冯华[1] 

机构地区：[1]第三军医大学西南医院神经外科,重庆400038

出　　处：《中华神经外科疾病研究杂志》2013年第6期527-530,共4页Chinese Journal of Neurosurgical Disease Research

摘　　要：目的探讨提高前颅底脑膜瘤全切率、降低死亡率和并发症的显微外科治疗策略。方法分析显微手术治疗的68例前颅底脑膜瘤的影像学资料、手术入路、手术技巧及疗效等资料,总结经验教训。结果肿瘤切除达到SimpsonⅠ级或Ⅱ级58例(85.29%),次全切除8例,部分切除2例;病理检查均证实为脑膜瘤;术后主要原有症状较术前改善64例(94.12%),无改善4例,术后早期出现并发症6例,死亡1例;随访6个月至5年,2例复发,二次手术切除。结论通过充分的术前准备,选择恰当的手术入路,依靠娴熟的显微外科手术技巧处理好手术细节,严密监测术中术后并发症,积极谨慎的切除前颅底脑膜瘤可以取得满意疗效。Objective To investigate the tream^nt strategies of meningiomas at anterior skull base to improve the resection rate, reduce the mortality and the complications. Methods The clinical data of 68 patients with meningiomas at anterior skull base who underwent microsurgery, such as image data, the operative approaches and surgical techniques, were analyzed retrospectively. Results According to Simpson classification of meningioma resection, 58 cases received grade I ~ ]I resection （85.29%）, 8 cases received subtotal resection, 2 cases received partial resection. Histopathology and immunohistochemistry confirmed the diagnosis of meningioma. Major symptoms of 64 cases （94.12% ） were improved after surgery, 4 cases received no improvement; the complications eccutred in 6 cases and one dead case. All the cases were followed up, ranging from 6 months to 5 years. Recurrence of meningiomas was observed in 2 cases. Conclusion The meningiomas at anterior skull base can be resected effectively by sufficient pre-opemtive preparation, skillful surgical techniques and monitoring of the complications.

关 键 词：前颅底 脑膜瘤 显微手术 

分 类 号：R739.45[医药卫生—肿瘤]