国内肝紫癜病临床特点分析  

Clinical characteristics of Chinese peliosis hepatis

作　　者：陆旭[1] 刘沛[1] 

机构地区：[1]中国医科大学附属第一医院传染科,沈阳110001

出　　处：《肝脏》2013年第11期725-727,共3页Chinese Hepatology

摘　　要：目的总结国内肝紫癜病的临床特点,提高临床医生对该病的认识。方法检索中国期刊全文数据库、万方全文数据库、维普全文数据库中1988年-2012年的全部文献,共收集确诊为肝紫癜病且有完整病例资料的患者22例。结果在22例患者中,男性8例,女性14例,平均发病年龄为(42±18)岁。部分患者无临床症状及体征。余患者主要症状包括腹胀、腹痛、乏力、纳差等,体征主要表现为肝大、脾大、腹部膨隆压痛、移动性浊音阳性等。实验室及影像学检查无特异性表现,诊断需依靠肝脏组织病理检查。结论肝紫癜病是一种罕见疾病,该病缺乏特异性的症状、体征及实验室检查结果,需通过肝脏病理明确诊断。Objective To summarize the clinical characteristics of Chinese peliosis hepatis,and to improve clinical physician’s recognition of the disease.Methods An online search was undertaken on China Journal Full Text Database（CJFD）,Wanfang Full Text Database,and VIP Full Text Database from 1988 to 2012.The study enrolled total 22 patients who were diagnosed with peliosis hepatics by liver biopsies.Results With an average age of 42±18 years old, 8 of 22 patients were males and 14 of 22 patients were females.Some patients had no clinical symptoms and physical signs.The main symptoms of other patients included abdominal distension,abdominal pain,fatigue,anorexia and so on. The main signs of patients included hepatomegaly,splenomegaly,abdominal tenderness,abdominal distention and shifting dullness positive.Laboratory and imaging examination showed no specific performance,and the diagnosis depended on liver biopsies.Conclusion Peliosis hepatis is a rare disease which lacks of specific symptoms,signs and examination.The diagnosis depends on liver biopsies.

关 键 词：肝紫癜病 临床特点 

分 类 号：R575[医药卫生—消化系统]