直肠癌浸润、转移、病理分期与中医辨证的相关性  

Association of Traditional Chinese Medicine Syndromes with Tumor Invasion, Metastasis,and Pathological Stages in Patients with Rectal Cancer

作　　者：周钟珩[1] 程宁昌[2] 

机构地区：[1]江苏省中医院放射科,江苏南京210019 [2]南京中医药大学第一临床医学院,江苏南京210019

出　　处：《安徽中医学院学报》2013年第6期33-35,共3页Journal of Anhui Traditional Chinese Medical College

摘　　要：目的探讨直肠癌浸润、转移、病理分期与中医辨证的相关性。方法采用前瞻性研究方法,基于TNM病理分期系统,对72例直肠癌患者的术前证型、肿瘤浸润程度、淋巴转移、远处转移、病理分期的关系进行统计分析。结果实证与虚证的肿瘤浸润程度比较,差异无统计学意义(P>0.05);湿热内蕴证的T1+T2期构成比明显多于其他证型(P<0.05,或P<0.01),T3+T4期构成比明显少于其他证型(P<0.05,或P<0.01)。虚证与实证的病理分期比较,差异具有统计学意义(P<0.01)。结论中医辨证与肿瘤浸润程度、远处转移、病理分期显著相关。Objective To investigate the association of traditional Chinese medicine （TCM） syndromes with tumor invasion, metastasis, and pathologica tive study was conducted in 72 patients with recta stages in patients with rectal cancer. Methods Prospec cancer, and statistical analysis was performed to investi gate the association of perioperative TCM syndromes with tumor invasion, lymph node metastasis, distant metastasis, and pathological stages （based on the TNM staging system）. Results There was no signifi- cant difference in the depth of tumor invasion between the patients with excess syndrome and deficiency syndrome （P〈0.05）. Compared With those with other TCM syndromes, the patients with syndrome of internal retention of damp-heat had a significantly higher proportion of T1/T2 cases （P〈0.05 or P〈0.01） anda significantly lower proportion of T3/T4 cases （P〈0. 05 or P〈0. 01）. There was significant difference in pathological stages between the patients with excess syndrome and deficiency syndrome （P〈 0.01）. Conclusion TCM syndromes are significantly associated with the tumor invasion, distant metasta- sis, and pathological stages in patients with rectal cancer.

关 键 词：直肠癌 浸润 转移 病理分期 证型 前瞻性研究 

分 类 号：R735.37[医药卫生—肿瘤]