肝动脉介入治疗对手术后复发性肝癌的疗效分析  

Clinical effect of hepatic artery interventional therapy for recurrent hepatocellular carcinoma

作　　者：沈炜[1] 

机构地区：[1]江苏省东南大学医学院附属江阴医院介入科,江阴214400

出　　处：《中国肿瘤临床与康复》2013年第12期1381-1383,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨肝动脉介入治疗对复发性肝癌患者的临床疗效。方法选取收治的复发性肝癌患者76例,依据治疗方法不同分为观察组(39例)和对照组(37例)。两组患者均给予肝动脉插管化疗栓塞治疗,观察组在此基础上再给予经皮瘤内无水酒精注射治疗。比较两组患者临床疗效、Karnofsky评分以及白细胞下降程度。结果观察组患者总有效率为64.1%,对照组患者总有效率为51.4%,差异有统计学意义(P<0.05)。观察组患者治疗后Karnofsky评分总增加率为61.5%,对照组为51.4%,差异有统计学意义(P<0.05);观察组患者治疗后白细胞总下降率为28.2%,对照组为48.6%,差异有统计学意义(P<0.05)。结论肝癌复发性患者肝动脉介入治疗临床疗效确切,能够明显改善患者Karnofsky评分,减少白细胞降低程度,改善患者生活质量。Objective To explore clinical effect of hepatic artery interventional therapy for recurrent hepatocellular carcinoma（ HCC）. Methods 76 patients with recurrent HCCwere divided into observation group（ 39 cases） and control group（ 37 cases） according to the treatments. Both groups were treated with transcatheter arterial chemoembolization therapy,The observation group received additional percutaneous ethanol injection therapy. Clinical effect,Karnofsky score and leukopenia reduction were compared. Results After the treatments,the total effective rate of observation group（ 64. 1%） was higher than that of control group（ 51. 4%）,the difference was statistically significant（ P〈0. 05）. The total increment rate of Karnofsky score of the observation group was statistically superier to that of the control group（ 51. 4%,P〈0. 05）. And compared with the total reduction rate of white blood of the control group（ 48. 6%）,the one of the observation group（ 28. 2%） was lower（ P〈0. 05）. Conclusions Hepatic artery interventional therapy for recurrent HCC earns definite therapeutic effect,significantly give rise to patients＇ Karnofsky score,decrease reduction rage of the white blood cells,and thus improve quality of life of patients.

关 键 词：癌 肝细胞 栓塞 治疗性 治疗结果 预后 

分 类 号：R735.7[医药卫生—肿瘤]