依达拉奉用于围术期脊髓保护的效果观察  

Effect Observation of Edaravone for Protection with Perioperative Spinal

作　　者：刘奕君[1] 莫桂煕 蔡树云[1] 

机构地区：[1]广东医学院附属医院,广东湛江524000

出　　处：《中国医药指南》2013年第35期307-308,共2页Guide of China Medicine

摘　　要：目的观察分析依达拉奉用于围术期脊髓保护的临床效果。方法选取我院接受减压内固定治疗的脊髓损伤患者共60例,依照入院顺序随机平均分为观察组与对照组,对照组常规方式予以减压内固定手术治疗,观察组在对照组基础上加用依达拉奉保护脊髓。结果观察组术后30min脑脊液自由基平均水平(57.9±5.18),与术前相比无统计学差异(P>0.05),且明显低于对照组同期水平(P<0.05)。观察组术后2周及3个月JOA评分均明显高于对照组(P<0.05)。结论依达拉奉用于围术期可有效控制脑脊液自由基水平、提升JOA分数,脊髓保护效果显著。Objective To observe the effect of edaravone for protection with perioperative spinal effect. Methods 60 cases of patients with spinal cord injury, divided into the observation group and the control group, the control group treated with decompression and internal fixation operation, the observation group based on the control group used edaravone to protect spinal cord .Results The average of free radicals in cerebrospinal fluid in observation group were lower than those of the control group30min after operation（P〈0.05）, the JOA score of observation group were higher 2 weeks and 3 months after operation（P〈0.05）. Conclusion The effect of edaravone protect spinal cord significantly,

关 键 词：依达拉奉 围术期 脊髓保护 

分 类 号：R744[医药卫生—神经病学与精神病学]