42例原发性皮肤恶性淋巴瘤分类的研究  

Study on The Classification of 42 Cases of Primary Cutaneous Malignant Lymphomas

作　　者：曾跃斌[1] 王琳[1] 周光平 李甘地[2] 

机构地区：[1]华西医科大学第一附属医院皮肤科 [2]华西医科大学第一附属医院病理科

出　　处：《中国皮肤性病学杂志》2000年第6期372-374,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的了解原发性皮肤恶性淋巴瘤（ＰＣＭＬ）的类型分布及临床病理特点。方法主要依据Ｗｉｌｌｅｍｚｅ等１９９４年提出的 ＰＣＭＬ分类标准对 ４２例 ＰＣＭＬ进行分类研究。结果①在 ＰＣＭＬ中，皮肤 Ｔ细胞淋巴瘤（ＣＴＣＬ）多见（６９．０％），其中草样肉芽肿（ＭＦ）占７ ２％。皮肤Ｂ细胞淋巴瘤（ＣＢＣＬ）较少见（３１．０％）。（２）ＰＣＭＬ中男女之比为２：１，中位发病年龄３７岁，ＣＴＣＬ的中位发病年龄小于ＣＢＣＬ（Ｐ＜０．０１），高度恶性ＰＣＭＬ的中位发病年龄小于低度恶性ＰＣＭＬ（Ｐ＜０．０１）。③临床上，ＭＦ可表现为红斑、斑块等非特异性皮损，而其它各类皮损均表现为无症状性皮肤结节、肿块。结论ＰＣＭＬ各类型具有不同的临床病理特点。Objective To investigate type distribution and clinicopathological feature of primary cutanoous malignant lym- phomas (PCML). Mathods 42 cases of PCML were classified mainly according to the classification of PCML propsed by Willemze et al in 1994. Results (1)Among of PCML, cutaneous T - cell lymphoma(CTCL) was more common(69. 0 % ).Cuta- neous B-cell lymphoma (CBCL) was fewer(31. 0 % ). (2)Among of the patients with PCML, The male-to-female ration was 2: 1 and the average age was 37 years. The average age of the CTCL was younger than that of the CBCL(P< 0. 01 ). The averge age of the high grade malignant PCML was younger than that of the low grade malignant PCML(P< 0. 01 ). (3)Clinically, MF pre- sented with non-specific skin lesion such as papule or plaque,Whereas these PCML other than MF presented with asymptomatic nodule or tumor. Conclusions There are different clinicopathological features in various subtypes of PCML respectively.

关 键 词：原发性 皮肤淋巴瘤 分类 临床病理 

分 类 号：R739.502[医药卫生—肿瘤] R733.402[医药卫生—临床医学]