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机构地区:[1]中国医学科学院 北京协和医学院 北京协和医院妇产科,北京100730 [2]浙江省台州市立医院妇科,台州318000 [3]中国医学科学院 北京协和医学院 北京协和医院病理科,北京100730
出 处:《癌症进展》2013年第6期592-595,共4页Oncology Progress
摘 要:目的 探讨该类肿瘤的临床特点、病理特征及治疗预后,总结外阴、阴道良性肿瘤的临床诊治经验.方法 回顾性分析236例外阴、阴道良性实性肿瘤患者的临床及病理资料.结果 外阴良性肿瘤177例,阴道良性肿瘤59例,所有患者均为单发,外阴良性肿瘤平均发病年龄为41.1 (1~73)岁,阴道良性肿瘤平均发病年龄为45.7(24 ~71)岁;97.2% (172/177)外阴良性肿瘤初发患者表现为外阴肿物,71.2% (42/59)阴道良性肿瘤患者在妇科检查时发现阴道肿物;外阴、阴道良性实质性肿瘤以平滑肌瘤、乳头状瘤、纤维瘤、色素痣等常见.61.6%(109/177)外阴良性肿瘤患者为色素痣,而在59例阴道良性肿瘤中,平滑肌瘤占71.2% (42/59).患者均采用局部病灶切除术,术后随访1~5年,外阴良性肿瘤未见复发,阴道良性肿瘤有3例(5.1%)出现术后复发.结论 外阴、阴道良性实性肿瘤术后预后较好,但仍有复发、恶变风险,提倡早日手术切除,术后需加强随访.Objective To study the clinical pathological features, histogenesis and prognosis of benign vulvar and va- ginal neoplasms, then summarize the clinical experience of treatment of these disease. Method The clinical and patholog- ical data of 236 patients with benign vulvar and vaginal neoplasms were analyzed retrospectively. Result There were 177 cases of benign vulvar neoplasms, and 59 cases of benign vaginal neoplasms. All the patients were with a single tumor, and the average onset age of benign vulvar neoplasms is 41.1 ( 1 - 73 ) years, while the average onset age of benign vaginal ne- oplasms is 45.7 (24 -71 ) years. Genital tumors were identified through gynecological examination in 97.2% ( 172/177 ) of the benign vulvar neoplasms patients and 71.2% (42/59) of the benign vaginal neoplasms patients. The most common benign solid neoplasms include leiomyoma, papilloma, fibroma and pigmented nevus. 61.6% (109/177) benign vulvar neoplasms were proved to be pigmented nevus, while among the 59 cases of benign vaginal neoplasms, 71.2% (42/59) were leiomyoma. All patients had had their localized lesions resected. There was no report on the recurrence of vulvar neo- plasms, while there were 3 cases (5.1% ) of benign vaginal neoplasms recurred during 1 - 5 years of postoperative follow- up. Conclusion The postoperative prognosis of benign vulvar and vaginal neoplasms is good, but the recurrence and ma-lignant transformation risks still exist. It is suggested that the lesion be resected as soon as possible in combination with fre- quent postoperative follow-up.
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