缺铁条件下酵母中铁转运转录水平的研究进展  

Advances of Gene Expression in Iron Transport Response to Iron Deprivation in Saccharomyces cerevisiae

作　　者：王俐勇[1] 赵君朋[1] 

机构地区：[1]首都医科大学医学实验与测试中心,北京100069

出　　处：《基因组学与应用生物学》2013年第6期815-819,共5页Genomics and Applied Biology

基　　金：北京市教委科技发展基金重点项目(KZ200710028013)资助

摘　　要：铁作为生物体内重要元素,在很多细胞功能以及生化过程中具有重要作用。尽管多数土壤中铁含量较为丰富,但在碱性或中性土壤中可以吸收利用的可溶性铁量却无法满足植物需要。在这种情况下所导致的缺铁胁迫不利于植物生长发育。本文从铁吸收系统的激活、胞内铁源的启动和铁相关代谢活动的调控三个方面阐述了酵母细胞中铁转运转录水平上的研究现状,最后展望了其发展前景。As an essential element, iron plays an important role in many cellular functions and biochemical processes. Although being generally abundant in most soil, soluble irons are deficient for most plants in alkaline or neutral soils. In this case, iron stress is full of adversity for plant growth. In this paper, we summarized the research progress on activation of iron uptake systems, mobilization of intracellular iron, and regulation of iron related metabolic activities in yeast cells. Future research prospects are also discussed.

关 键 词：铁转运 转录水平 酵母 

分 类 号：Q78[生物学—分子生物学]