食管癌高低发区贲门癌发病对比分析  

Comparison of gastric cardiac cancer incidence between areas with low and high esophageal cancer incidence

作　　者：魏矿荣[1] 陈志峰[2] 彭侠彪[3] 李东方 宋国慧 梁智恒[1] 欧志雄[1] 

机构地区：[1]中山大学附属中山医院肿瘤研究所,广东中山528400 [2]河北医科大学第四医院肿瘤研究所防治室,河北石家庄050021 [3]中山大学附属中山医院消化内科,广东中山528400 [4]河北磁县肿瘤医院肿瘤研究所,河北磁县056500

出　　处：《现代肿瘤医学》2014年第1期59-63,共5页Journal of Modern Oncology

基　　金：中山市科委基金资助项目(编号:20102A055);中山市人民医院科研基金资助项目(编号:2013003)

摘　　要：目的:分析食管癌高低发区贲门癌发病的特点和异同,为贲门癌防治提供科学依据。方法:收集、整理1988-2007年食管癌低发区广东中山市与高发区河北磁县全人群肿瘤登记中的贲门癌发病资料,比较其发病数、粗率、中国与世界标化发病率(简称中标率与世标率)、构成比和发病趋势等指标。结果:1988-2007年广东中山与河北磁县贲门癌世标发病率分别为0.50/105和23.87/105,磁县发病远高于中山,是中山的47.74倍,两地贲门癌发病均呈上升趋势,尤以河北磁县显著。此外,广东中山市贲门癌男女发病数比例高于河北磁县。结论:虽然期间两地贲门癌发病均呈上升趋势,但其贲门癌发病存在显著差异,食管癌高发区河北磁县贲门癌发病远高于食管癌低发区广东中山,且其发病趋势与食管癌相反,而中山相同。Objective：To explore the characteristics and difference of gastric cardiac cancer incidence in and between areas with high and low esophageal cancer incidence,and to provide scientific information for its prevention and control.Methods：Gastric cardiac cancer incidence data in 1988-2007 of Zhongshan City in Canton with low esophageal cancer incidence and Cixian County in Hebei Province with high esophageal cancer incidence came from population-based Zhongshan and Cixian Cancer Registries respectively,were collected and collated.Such indices as its incident numbers,crude and age-adjusted rates,proportional ratios and trends were calculated and analyzed.Results：During 1988-2007,gastric cardiac cancer world age-adjusted incidence rate in Cixian County of Hebei Province was 47.74 time than that of Zhongshan City in Canton,which were 23.87/105 and 0.50/105 respectively,both showed obviously increasing trends in 1988-2007 especially for Cixian County.Moreover,incident number of sex ratio in Zhongshan was higher than that of Cixian.Conclusion：Although increasing incident trends had been seen in both areas,obviously gastric cardiac cancer incident difference existed between areas with high and low esophageal cancer incidence.Its incidence rate in Cixian with high esophageal cancer incidence was much higher than that of Zhongshan with low esophageal cancer incidence,and its incident trend was opposite with higher esophageal cancer incidence in Cixian,but consistent with esophageal cancer incidence in Zhongshan.

关 键 词：贲门肿瘤 发病 食管肿瘤 

分 类 号：R735.1[医药卫生—肿瘤] R735.2[医药卫生—临床医学]