滴定量热法研究氨基酸羧基质子化反应  

Titration Calorimetry Study on the Protonation Reaction of α-Carboxyl Group of Ammo Acids

作　　者：张保林[1] 王文清[1] 李忠[1] 陶祖贻[2] 

机构地区：[1]北京大学技术物理系,北京100871 [2]兰州大学现代物理系

出　　处：《高等学校化学学报》1991年第11期1522-1523,共2页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金

摘　　要：氨基酸是典型的两性物质,其羧基质子化常数已有报道,文献结果大都由pH电位法得到,而对氨基酸光学异构体(D、L、DL)的对比研究甚少,为检验光学活性起源理论中提出的D与L分子间的能量差异,我们曾用微量量热技术观察了苯丙氨酸、亮氨酸。The thermodynamic functions of protonation reactions of α-carboxyl group of twelvekinds of amino acids--alanine?valine, lysine, leucine, phenylalanine, methionine, trypto-phan, threonine, serine, arginine, glutamic acid and glycine, have been determined by titration calorimetry combined with computer fit program. The differences between△H, AG, lgK, △S of the protonation reactions of amino acids have been reported. By comparison with pH titration method, it is simple, rapid and would be obtained simultaneously the total thermodynamic functions-IgK, △H, △6G and △S.

关 键 词：氨基酸 质子化 滴定量热法 

分 类 号：O629.711[理学—有机化学]