肝淀粉样变性的显微和超微结构观察  

Study of the hepatic amyloidosis by microscope

作　　者：吴敏霞[1] 陈虹[2] 周琳瑛[1] 钟秀容[1] 

机构地区：[1]福建医科大学基础医学院病理学系电镜室,福州350004 [2]福建医科大学附属第一医院病理科,福州350004

出　　处：《安徽医科大学学报》2014年第1期113-114,共2页Acta Universitatis Medicinalis Anhui

基　　金：福建医科大学苗圃科研基金(编号:2010MP027);福建省教育厅课题(编号:JA07105)

摘　　要：应用HE染色、刚果红染色、高锰酸钾氧化刚果红染色、透射式电子显微镜观察病肝组织的显微及超微结构变化。结果显示,光镜下淀粉样物质可逐渐沉积于窦周间隙、肝细胞间、汇管区,这些受累的区域无细胞或细胞过少;电镜下观察肝细胞间沉着大量淀粉样物质,肝细胞萎缩甚至崩解,细胞器消失,出现裸核。The microstructure and the ultrastructrue of the hepatic amyloidosis were studied with HE stain,Congo red and its permanganate-oxygenated stain, as well as transmission electron microscope. The amyloid deposition was mainly located at sinusoida and portal area. Liver cells atrophied and were gradually replaced with amyloid material and appeared naked nucleus.

关 键 词：淀粉样变性 超微结构 电镜观察 

分 类 号：R742.4[医药卫生—神经病学与精神病学]