应用EDSS系统评价高压氧治疗多发性硬化患者的临床疗效  

EDSS is available in assessment the effects of hyperbaric oxygen in multiple sclerosis

作　　者：张皓[1] 刘诗翔[1] 孔繁一[1] 胡炜娜[1] 贺艳琴[1] 

机构地区：[1]成都军区昆明总医院神经内科,云南昆明650032

出　　处：《西部医学》2014年第1期74-76,共3页Medical Journal of West China

摘　　要：目的观察高压氧(Hyperbaric Oxygen,HBO)对多发性硬化(Multiple sclerosis,MS)患者神经功能改善的临床疗效。方法采用随机双盲抽样分组将101例经过磁共振、腰椎穿刺术、诱发电位确诊的多发性硬化患者分为对照组50例和病例组51例,两组患者除常规治疗外,对照组给予氧仓不加压吸氧;病例组则给予高压氧治疗,并应用EDSS(Expanded disability status scale,EDSS)评分评估MS患者高压氧治疗前后的神经功能情况。结果高压氧治疗组EDSS评分改善情况明显优于对照组(P<0.05)。结论早期、规律的应用高压氧对多发性硬化患者的治疗有明显的临床疗效。Objective To observe the improvement of Multiple Sclerosis （Multiple sclerosis, MS） neurological function by after treatment by Hyperbaric Oxygen. Methods Adopt randomized double-blind sampling a group of 101 patients who diagnosed by MRI, lumbar puncture and evoked potential as Multiple Sclerosis divided into a control group of 50 patients, case group of 51 patients, use the EDSS （Expanded Disability status scale, EDSS） score to assess nerve function before and after the hyperbaric oxygen therapy. Results The improvement of EDSS score of case group signifi- cantly better than the control group. Conclusion The early, regular use of hyperbaric oxygen in the treatment of multi- ple sclerosis has a clear benefit.

关 键 词：多发性硬化 高压氧 EDSS评分 

分 类 号：R744.51[医药卫生—神经病学与精神病学]