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机构地区:[1]复旦大学附属华山医院北院中西医结合科,上海市201907 [2]上海中医药大学附属曙光医院,上海市201203 [3]同济医院,上海市200065
出 处:《老年医学与保健》2013年第6期397-401,共5页Geriatrics & Health Care
摘 要:目的评价扶正固元法干预缺血性中风恢复期的临床疗效。方法采用随机数字法将72例患者分别纳入至对照组与干预组。对照组采用西医常规治疗,干预组在对照组的治疗基础上加服扶正固元方,2W为一个疗程,连续服用2个疗程。治疗前后分别观察NIHSS评分、Barthel指数、MRS、神经功能缺损积分疗效分级评定以及中医症状记分和综合疗效指数与缺血性中风发病相关因素相关性的判定。结果与对照组2W后、3m后分别进行比较,干预组NIHSS评分与MRS降低、Barthel指数与中医症状记分增高,均具有统计学意义(P〈0.01);按照神经功能缺损积分疗效评定分级标准进行分级,干预组较对照组显愈率与有效率显著提高(P〈O.01);且经统计分析,疗效指数与年龄、伴发病积分、既往史积分呈负相关,与病程、中医证候疗效指数无相关性关系。结论扶正固元方具有能够改善缺血性中风恢复期患者临床症状,提高日常生活活动能力的作用,临床疗效得以提高。Objective To evaluate the clinic efficacy of the approach of reinforce body resistance to consolidate vigor after intervening in ischemic stroke patients at their recovery stage. Methods 72 patients were randomly divided into an in- tervention group and a control group. Both groups were given basic treatment. At this basis, the patients in the intervention group were given Chinese decoction, namely prescription for reinforcing body resistance to consolidate vigor for two courses of treatment. One course consists of two weeks. The scores of NIHSS, Barthel index, MRS, Classification efficacy assessment of neurological deficit scores, and the correlation judgments between the TCM symptom scores, comprehensive efficacy index and the factors related to ischemic stroke patients were assessed before treatment, after 2 weeks, and 3 months admission of the trial, respectively. Results Compare with the control group after 2 weeks' and 3 months' inter- vention, the NIHSS and MRS were decreased, while the BI index and the symptom score of TCM were increased in the intervention group, and both display the statistical significance (P〈0.01). According to the classification of efficacy as- sessment of neurological deficit scores, the obvious curative rate and curative efficacy in the intervention group were higher than those in the control group, and they still appear statistical significance (P〈0.01). Through statistical analysis, the efficacy index has negative correlation with the score of concomitant disease, the past history and age, while it has no cor- relation with the course of disease and the efficacy index of TCM symptom. Conclusions The prescription for reinforce body resistance to consolidate vigor could improve the clinical symptoms and activities of daily living of the ischemic stroke patients, and consequently the clinic efficacy was increased.
分 类 号:R743.3[医药卫生—神经病学与精神病学]
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