肝宁胶囊的质量标准研究  

Study on Quality Standard for Ganning Capsules

作　　者：张海 张力 李钦青[2] 阎文斌 季新燕[2] 刘亚明[2] 

机构地区：[1]山西仁源堂药业有限公司,山西太原030043 [2]山西中医学院,山西太原030024

出　　处：《山西中医学院学报》2013年第5期31-32,共2页Journal of Shanxi College of Traditional Chinese Medicine

基　　金：国家自然基金面上资助项目(81173381)

摘　　要：目的:对肝宁胶囊质量标准进行研究。方法:采用薄层色谱法对处方中的紫草进行定性鉴别;采用气相色谱法对处方中的斑蝥素进行含量测定。结果:在薄层色谱中可检出紫草的特征斑点;斑蝥素在0.013 8μg^0.124 2μg(r=0.999 9)范围内线性关系良好,回收率为98.466%(RSD=1.92%,n=5)。结论:本方法简便可行、重复性好,能有效控制该制剂的质量。Objective：To study the quality standard for Ganning capsules. Methods：Radix Arnebiae in prescription was i- dentified by TLC, and the content of eantharidin in prescription was detected by HPLC. Results ： The characteristic spots of Radix Arnebiae were identified by TLC. Cantharidin showed a good linear relationship at a range of 0.013 8 μg-0.124 2 μg （r=0.999 9）. The average recovery was 98.466%（RSD=1.92% ,n=5）. Conclution ：The methods are available with a good reproducibility and can control the quality of this preparation effectively.

关 键 词：肝宁胶囊 质量标准 斑蝥素 GC 

分 类 号：R285.5[医药卫生—中药学]