正畸牙移动中牙周膜的力学-生物学行为研究进展  

Advances in mechano-biological behavior of peridontal ligament during orthodontic tooth movement

作　　者：颜艳[1] 杨力[2] 

机构地区：[1]南开大学口腔医院暨天津市口腔医院中心实验室,天津300041 [2]重庆大学生物工程学院,生物流变科学与技术教育部重点实验室,400030

出　　处：《国际生物医学工程杂志》2013年第6期367-370,380,共5页International Journal of Biomedical Engineering

摘　　要：正畸牙移动（OTM）是一个相当复杂的力学-生物学过程,是通过力学手段使牙周组织发生改建而实现的.牙周膜作为连接牙槽骨与牙骨质的结缔组织,在对正畸力的感受和传导中起着非常重要的作用;同时,其在OTM过程中敏感的生物力学反应是介导和调控牙周组织发生改建的关键因素.就牙周膜在OTM过程中的具体作用及其力学-生物学行为作一综述.结合近年来最新的研究成果,从组织、细胞及分子水平阐明了牙周膜在OTM中的力学响应及生物学行为机制.Orthodontic tooth movement （OTM） is a very complicate mechano-biological procedure which is accomplished by the remodeling of periodontal tissues via orthodontic force.As the connective tissue between alveolar bone and cementum,periodontal ligament plays a vital role in the response and conduction of orthodontic force.The susceptible response of periodontal ligament to orthodontic force during OTM is a critical factor on inducing and modulating periodontal tissue restitution.This article reviews the concrete role of periodontal ligament and its mechano-biological behavior during OTM,discusses its mechanical response and biological mechanism respectively on histological,cellular and moleucular levels.

关 键 词：正畸牙移动 牙周膜 生物力学 牙周组织改建 

分 类 号：R783.5[医药卫生—口腔医学] R318.01[医药卫生—临床医学]