长沙版蒙特利尔认知评估量表在血管性认知功能障碍中应用的初步研究  

Preliminary study of application of Changsha version of Montreal Cognitive Assessment Scale in vascular cognitive impairment

作　　者：袁正洲[1] 李作孝[1] 李经伦[1] 尹俊雄[2] 吕志宇[1] 赖成虹[3] 

机构地区：[1]泸州医学院附属医院神经内科,四川泸州646000 [2]四川省人民医院神经内科,成都610072 [3]四川省内江市第一人民医院神经内科,641000

出　　处：《重庆医学》2014年第2期132-135,共4页Chongqing medicine

摘　　要：目的探讨长沙版蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)在脑梗死后血管认知障碍(vascular cognitive impairment,VCI)评估中的价值。方法选择112例临床诊断为脑梗死患者,分为认知功能正常组(NC组)和VCI组。使用长沙版MoCA及迷你智力状态量表(mini mental state examination,MMSE)检测其认知功能,进行两种量表的关联性分析及初步探讨长沙版MoCA的截断值。结果 VCI组长沙版MoCA总评分及MMSE总评分[分别为(15.12±4.60)、(20.44±3.22)分]均低于NC组[分别为(22.75±1.79)、(25.21±1.74)分],差异有统计学意义(P<0.05);长沙版MoCA总评分与MMSE总评分呈正相关(r=0.84,P<0.01);长沙版MoCA最佳截断值分为20/21,此时其灵敏度及特异度分别为92%、95%。结论长沙版MoCA能很好地筛查VCI,具有较高的筛查价值,其最佳截断值为20/21。Objective To investigate the value of the Changsha version of the Montreal Cognitive Assessment Scale（MoCA） in the assessment of vascular cognitive impairment after cerebral infarction. Methods 112 cases of clinically diagnosed cerebral infarc- tion were selected and divided into the normal cognition（NC） group and vascular cognitive impairment（VCI） group. The Changsha version of MoCA and the mini-mental state examination（MMSE） were adopted to detect the cognitive function, the correlation of two scales was analyzed and the cutoff values of the Changsha version of MoCA were preliminarily studied. Results The total scores of the Changsha version of MoCA and MMSE in the VCI group were 15. 12~4. 60 and 20.44＋3.22 respectively,which were lower than 22.75＋1.79 and 25. 21 ＋ 1. 74 in the NC group, the difference had statistical significance（P〈Z0.05）;the total scores of the Changsha version of MoCA was positively correlated with the total scores of MMSE（r=0.84,P〈0.01） ;the best cut- off value of the Changsha version of MoCA was 20/21 ,the sensitivity and specificity were 92% and 95% respectively. Conclusion The Changsha version of MoCA can screen VCI well and has a high screening value,and its optimal cutoff value is 20/21.

关 键 词：卒中 认知障碍 痴呆 长沙版蒙特利尔认知评估量表 

分 类 号：R749.1[医药卫生—神经病学与精神病学]