NRS-2002评估术前不同营养状态对结直肠癌患者生存质量的影响  

The Impact of The Preoperative Nutritional Status on Quality of Life of Colorectal Cancer Patients

作　　者：李智[1,2] 张雅玲[2] 汪晓东[1] 韦诗友[2] 黄明君[1] 李卡[1] 

机构地区：[1]四川大学华西医院胃肠外科中心,四川成都610041 [2]四川大学华西临床医学院/华西医院,四川成都610041

出　　处：《中国普外基础与临床杂志》2014年第1期41-45,共5页Chinese Journal of Bases and Clinics In General Surgery

基　　金：四川省科技厅支撑项目(项目编号:2012SZ0039);四川大学科研训练计划(项目编号:20120705)~~

摘　　要：目的探讨术前不同营养状态对结直肠癌患者生存质量的影响。方法选取2012年9月至2012年12月期间四川大学华西医院胃肠外科中心收治的结直肠癌患者,采用欧洲营养风险筛查量表(nutritional risk screening 2002,NRS-2002)对其术前营养状态进行评分,同时运用欧洲癌症研究与治疗组织的生命质量核心量表(EORTC QLQ-C30)评估患者术后1个月的生存质量情况。结果本研究共纳入患者44例,根据术前营养状态评分分为2组:轻度营养风险组(1分)27例及中重度营养风险组(≥2分)17例。2组患者的基线资料中,中重度营养风险组患者年龄明显大于轻度营养风险组患者(P=0.001),而性别(P=0.718)、肿瘤TNM分期(P=0.302)、分化程度(P=0.564)、术前合并症(P=0.070)、术后并发症〔NS(无统计学意义)〕及造口(P=0.786)方面,2组患者间的差异均无统计学意义。生存质量方面,2组患者在功能领域、症状领域、单个条目及总体健康情况方面的差异均无统计学意义(P>0.05)。结论未能得出结直肠癌患者术前营养状态与其生存质量有关。这可能与本研究样本量较小、评估时间短且时间点单一有关,因此有待进一步的大样本、应用多种评估方式和选取多个不同时间点来更客观地评估结直肠癌患者营养状态对生存质量的影响。Objective To explore the impact of the preoperative nutritional status on quality of life of colorectal cancer patients. Methods In this study, patients diagnosed definitely as colorectal cancer were enrolled from September 2012 to December 2012 in this hospital. NRS-2002 was used to assess the preoperative nutritional status, and QLQ-C30 was used to assess the quality of life. Results Forty-four patients were enrolled in this study and divided into two groups based on NRS-2002 preoperative nutritional status evaluation scores： mild nutritional risk group had 27 patients who got 1 point, and moderate-severe nutritional risk group had 17 patients who got 2 point or over it. Patients in moderate- severe nutritional risk group were significantly older than the mild nutritional risk group （P=0. 001）, but there were no statistical differences between the two groups in gender （P=0. 718）, TNM stage （P=0. 302）, differentiation degree （P=0. 564）, preoperative medical complications （P=0. 070）, postoperative complications [NS （not significant） ], and stoma （P=0. 786）. There were no statistical differences between the two groups in quality of life, too （P〉0. 05）. Conclusions This study don＇t get the conclusion that there is any relationship between nutritional status and quality of life of the colorectal cancer patients. And maybe it is effected by the too small sample size and single time of accessing. Therefore, the further research by expanding sample size, using more kinds of assessment tools, and selecting different time to explore theimpact of the preoperative nutritional status on quality of life of colorectal cancer patients are necessary.

关 键 词：营养状态 生存质量 结直肠癌 

分 类 号：R735.3[医药卫生—肿瘤] R730.7[医药卫生—临床医学]