肾嫌色细胞癌29例临床分析  

Chromophobe renal cell carcinoma:clinical analysis and review of 29 cases

作　　者：常小峰[1] 连惠波[1] 赵晓智[1] 刘铁石[1] 李笑弓[1] 张古田[1] 甘卫东[1] 郭宏骞[1] 

机构地区：[1]南京大学医学院附属鼓楼医院泌尿外科,江苏南京210008

出　　处：《现代泌尿外科杂志》2014年第1期45-47,共3页Journal of Modern Urology

摘　　要：目的 探讨肾嫌色细胞癌的临床特点，提高其临床诊治水平。方法 回顾性分析2006年6月至2012年4月期间收治的29例肾嫌色细胞癌患者的临床资料，包括临床表现、影像学检查、治疗方法、病理分期和随访等。结果 29例患者均缺乏典型的临床症状，术前影像学检查亦未发现特异性表现。16例行根治性肾切除术，其余13例行保留肾单位手术，病理分期： pT 1 N 0 M 0 27例，pT 2 N 0 M 0 2 例。29例患者均获得随访，随访13-72个月，平均（35.0±7.2）个月，29例均无瘤生存。结论 肾嫌色细胞癌是肾细胞癌的一个独立类型，CT和B超检查缺乏特异性表现，主要通过病理学进行诊断，但CT表现与常见的肾透明细胞癌有所不同，手术切除是治疗肾嫌色细胞癌的首选方法，其预后较好。Objective To explore the clinical features of chromophobe renal cell carcinoma （CRCC） in order to improve its diagnosis and treatment. Methods Clinical data of 29 patients with CRCC treated during June 2006 and April 2012 were retrospectively analyzed, including clinical manifestations, imaging examinations, treatment models, pTNM stages and follow- up results. Results No cases had obvious clinical and preoperative imaging presentation. 16 patients underwent radical ne- phrectomy and 13 received nephron sparing surgery. Postoperative pathological findings confirmed the diagnosis of CRCC. The pTNM stages of the tumor were as follows., pT1NoM0 in 27 and pT2NoM0in 2 cases. During the follow-up of 13 to 72 months, mean 35 months, all 29 cases survived tumor free. Ooncltisions Chromophobe renal cell carcinoma is an uncommon morpho- logical subtype of renal cell carcinoma with good prognosis. Confirmed diagnosis depends on its typical pathological feature, while radical nephrectomy is the first choice for the treatment.

关 键 词：肾细胞癌 肾嫌色细胞癌 诊断 预后 

分 类 号：R737.11[医药卫生—肿瘤]