颅内血管周细胞瘤的影像学特征与病理对照研究  

Study on imaging features of intracranial hemangiopericytoma correlated with pathology

作　　者：陈明[1] 李凤[1] 刘春英[1] 熊小明[2] 韩福刚[1] 杨述根[1] 兰永树[1] 

机构地区：[1]泸州医学院附属医院放射科,四川646000 [2]泸州医学院附属医院病理科,四川646000

出　　处：《放射学实践》2014年第1期49-52,共4页Radiologic Practice

摘　　要：目的:探讨颅内血管周细胞瘤(HPC)的影像及病理特征,旨在提高对HPC的认识及诊断符合率。方法:搜集经手术病理及免疫组化证实的9例HPC病例,回顾性分析其CT、CTA及MRI表现,并与手术病理结果进行对照分析。结果:9例HPC均为单发病灶,具有颅内脑外肿瘤的征象,瘤周多有轻中度水肿,7例以窄基底与硬脑膜相连;增强扫描病灶明显强化,2例见"脑膜尾征",CTA可显示瘤体及瘤周丰富的血管影。9例免疫组化均显示波形蛋白(Vim)、CD34及CD99阳性,5例增殖细胞抗原Ki-67表达5%。结论:颅内血管周细胞瘤具有一定的影像学特征,分析其特点有助于提高术前诊断符合率,但确诊需依赖于病理及免疫组化检查。Objective：To study the imaging and pathological features of intracranial hemangiopericytoma （HPC）, so as to improve the knowledge and diagnostic accuracy of this disease. Methods：The CT,CT angiography and MRI findings of 9 cases with surgery and pathology proven intracranial HPC also with immuno-histochemistry examination were analyzed retrospectively and correlated with pathologic findings. Results： All of the 9 cases were showed as solitary lesion and located within the skull and outside of the brain,mild/moderate peri-tumoral edema could be assessed. 7 cases showed a narrow du- ral attachment. Marked enhancement was showed after contrast administration. Dural tail sign was revealed in 2 cases. Rich blood supply was seen within and adjacent to the tumor on CT angiography. All of the 9 cases had positive vimentin,CD34 and CD99 expression; proliferating cell nuclear antigen Ki-67 expression was 5% in 5 cases. Conclusion： Certain imaging characteristics of intracranial HPC could be revealed,which are helpful in preoperative diagnosis,but the final definite diag- nosis depends on pathology and immunohistochemical examination.

关 键 词：血管外皮细胞瘤 磁共振成像 体层摄影术 X线计算机 免疫组织化学 

分 类 号：R739.4[医药卫生—肿瘤] R814.42[医药卫生—临床医学]