肺孤立性磨玻璃密度结节的超高分辨力CT表现及与病理的相关性  

Study on solitary pulmonary ground-glass opacity nodule with ultra high resolution CT correlated with pathology

作　　者：陈群慧[1] 叶晓丹[1] 朱莉[1] 江一峰[1] 邵晋晨[2] 张杰[2] 李志明[3] 叶剑定[1] 

机构地区：[1]上海交通大学附属胸科医院放射科,上海200030 [2]上海交通大学附属胸科医院病理科,上海200030 [3]上海交通大学附属胸科医院设备科,上海200030

出　　处：《放射学实践》2014年第1期57-60,共4页Radiologic Practice

基　　金：上海市卫生局科研课题(No.20114189);上海市科学技术委员会课题(No.124119a0100)

摘　　要：目的:探讨肺孤立性磨玻璃密度结节的超高分辨力CT表现及与病理的相关性。方法:搜集经超高分辨力CT(UHRCT)检出并有病理结果的孤立性肺部磨玻璃密度结节(fGGN)72例,72例病灶最大径均≤2cm,回顾性分析其UHRCT表现,并与病理进行对照研究。结果:72例fGGN中纯磨玻璃密度结节(pGGN)20例,混合磨玻璃密度结节(mGGN)52例。20例pGGN中良性病变8例(40%,8/20),其中炎症3例,局灶纤维化3例,间质或肺泡上皮增生2例;不典型腺瘤样增生(AAH)6例(30%,6/20),细支气管肺泡癌(BAC)6例(30%,6/20)。52例mGGN中良性病变2例(3.85%,2/52),其中慢性炎症1例,肺泡内出血1例;恶性病变50例(96.15%,50/52),其中BAC10例,含BAC的腺癌35例,不含BAC的腺癌5例。结论:超高分辨力CT影像上,pGGN的病理诊断以良性病变、AAH或BAC为主,而mGGN则大多为BAC及肺小腺癌。Objective：To investigate ultra high resolution CT （UHRCT） findings of solitary pulmonary ground glass opacity （GGO） nodule correlating with pathology. Methods： 72 pathologically proved focal ground glass opacity （fGGO） nodules detected by UHRCT were recruited, with the maximum diameter ≤2cm. The UHRCT findings were retrospectively analyzed and correlated with pathology. Results：Of the 72 fGGO nodules,there were 20 pure GGO （pGGO） and 52 mixed GGO （mGGO）. 8 （40% ,8/20） were benign lesions among the 20 pGGO nodules （40% ,8/20） ,including inflammation （n= 3 ）, focal fibrosis （n= 3） interstitial or alveolar epithelial hyperplasia （n= 2） ; six （30 %, 6/20） were atypical hyperplasia; six （30 %, 6/20） were bronchilolalveolar carcinoma （BAC）. There were 2 cases （3.85 %,2/52） of benign lesions among 52 ca- ses of mGGO,including chronic inflammation,and alveolar hemorrhage for one case each;50 cases （96. 15% ,50/52） of mG- GO nodules were malignant lesions,including BAC （n= 10）,small pulmonary adenocarcinoma with BAC components （n= 35）, and small pulmonary adenocarcinoma without BAC components （n= 5）. Concluslon：The pathology of pGGO nodules on UHRCT were mainly benign lesions, AAH or BAC;most of the mGGO nodules were BAC and small pulmonary adenocarci- noma.

关 键 词：磨玻璃密度结节 肺肿瘤 体层摄影术 X线计算机 病理学 

分 类 号：R734.2[医药卫生—肿瘤]