儿童期受虐待经历与精神分裂症相关性的问卷调查  

Early life stress and schizophrenia：a retrospective case-control study

作　　者：曹世林[1] 田国强[1] 梁胜林[1] 蒋海潮[1] 甘建光 钱超[1] 徐政权[1] 

机构地区：[1]浙江省绍兴市第七人民医院精神科,312000

出　　处：《中华全科医师杂志》2014年第1期67-69,共3页Chinese Journal of General Practitioners

基　　金：绍兴市科技计划项目（重点科研项目-社会发展项目）

摘　　要：对2011年10月至2012年10月收治的105例首发精神分裂症患者（男/女为51/54例）以儿童期虐待问卷（CTQ-SF）调查儿童期受虐待事件,并以99例正常者为对照（男/女为51/48例）.Binary logistic回归分析显示,最后进入方程的自变量为情感虐待和情感忽视（β值分别为0.630和0.270,均P＜0.05）.精神分裂症患者生命早期可能经历了更多的负性生活事件,尤其是情感虐待和情感忽视,这可能对成年后患精神分裂症有重要影响.A total of 105 patients with first-episode schizophrenia （male = 51, female = 54） and 99 normal eontrols （male = 51, female -48 ） were included into this retrospective ease-control study. Childhood trauma questionnaire-28 item short form （CTQ-SF） was used to assess the experience of ehildhood abuse. The result of binalT logistic regression showed that emotional abuse （ β = 0. 630, P 〈 0. 05 ） and emotional negleet（β = 0. 270, P 〈 0. 05 ） were included into the final model of predicting schizophrenia. It indicates that patients with first-episode schizophrenia experienced more early life stress than controls. Particularly emotional abuse and emotional neglect may play important roles in the onset of schizophrenia.

关 键 词：儿童期受虐待经历 精神分裂症 

分 类 号：R749.3[医药卫生—神经病学与精神病学]