藤梨根的化学成分研究  

Chemical Constituents from the Roots of Actinidia chinensis

作　　者：赫军[1] 马秉智[1] 赵铁[1] 王巍[1] 魏凤玲[1] 陆进[1] 张相林[1] 

机构地区：[1]中日友好医院药学部,北京100029

出　　处：《中国药学杂志》2014年第3期184-186,共3页Chinese Pharmaceutical Journal

摘　　要：目的 研究藤梨根（Actinidia chinensis root）的化学成分。方法 利用各种色谱法进行分离, 根据理化性质和波谱数据鉴定结构。结果 从藤梨根的水提取物中分离得到8个酚类成分, 分别鉴定为（-）-表儿茶素（1）、（＋）-儿茶素（2）、秦皮素（3）、秦皮乙素（4）、原儿茶醛（5）、（-）-表儿茶素-5-O-β-D-吡喃葡萄糖苷（6）、erythro-1, 2-bis-（4-hydroxy-3-methoxyphenyl）-1, 3-propanediol（7）、threo-1, 2-bis-（4-hydroxy-3-methoxyphenyl）-1, 3- propanediol（8）。结论 化合物3~8为从该植物中首次分离得到。OBJECTIVE To investigate the chemical constituents from the roots of Actinidia chinensis. METHODS The compounds were isolated and purified by column chromatography and their structures were elucidated by spectroscopic methods. RESULTS Eight compounds were obtained from the aqueous extract of the roots of Actinidia chinensis.. The structures were determined as（-）-epi-catechin（1）, （＋）-catechin（2）, fraxetin（3）, escaletin（4）, protocatechuic aldehyde（5）, （-）-epi-catechin-5-O-β-D-glucopyranoside（6）, erythro-1, 2-bis-（4-hydroxy-3-methoxyphenyl）-1, 3-propanediol（7）, and threo-1, 2-bis-（4-hydroxy-3-methoxyphenyl）-1, 3-propanediol（8）. CONCLUSION Compounds 3-8 are isolated from the roots of Actinidia chinensis for the first time.

关 键 词：藤梨根 水提取物 酚类化合物 结构鉴定 (-)-表儿茶素 (+)-儿茶素 秦皮素 

分 类 号：R284.1[医药卫生—中药学]