非小细胞肺癌患者血小板增多与预后关系的临床研究  

The correlation between thrombocytosis and clinicopathological in patients with NSCLC

作　　者：李承慧[1] 段爱雄[1] 汪志求[1] 江恕 

机构地区：[1]安徽医科大学附属安庆医院肿瘤内科,安徽安庆246000

出　　处：《现代肿瘤医学》2014年第2期329-331,共3页Journal of Modern Oncology

摘　　要：目的:研究非小细胞肺癌(non-small cell lung cancer,NSCLC)患者血小板增多与临床病理因素和预后的关系。方法:回顾性分析2008年-2010年我院收治的70例非小细胞肺癌患者的临床及病理资料,33例合并血小板增多。结果:高血小板症与NSCLC的分期有关,Ⅰb期、Ⅱ期和Ⅲa期的发生率分别为21.05%、46.67%和71.43%(P<0.05)。高血小板症与病理类型、分化程度均无相关性;单因素分析显示高血小板症预后差(P=0.000),TNM分期增加预后越差(P=0.0029)。Cox多因素分析显示高血小板症和TNM分期具有独立预后价值(P<0.05)。结论:高血小板症与NSCLC的TNM分期有关,是影响NSCLC患者生存的独立预后因素。Objectlve：To study the prevalence of throlnbocytosis in patients with NSCLC and its correlation with elinieopathologieul features. Methods： Seventy patients of NSCLC were retrospectively analyzed. Of them there were 34 eases with increased platelet count. Results：Throlnboeytosis was related to TNM stage,throlnboeytosis of Ib stage, Ⅱ stage, Ⅲ. stage were found in 21.05% ,46.67% ,71.43% （P=0. 006） , but not related to histological type and differentiation. The univariate analysis showed that threlnbocytosis and TNM stage were related with survivul period（P=0. 000,P=0. 0029 ）. The multivariate analysis with Cox hazard model showed throlnboeytosis and TNM could be indicators for the prognosis of patients with NSCLC. Conclusion：Throlnbocytosis was related to TNM stage,and is an independent prognostic indicator of survival in patients with NSCLC.

关 键 词：高血小板症 预后 非小细胞肺癌 

分 类 号：R734.2[医药卫生—肿瘤]