晚期肿瘤合并恶性肠梗阻的预后分析  

Prognostic analysis in patients with non-curative stage IV cancer and malignant bowel obstruction

作　　者：王阿曼[1] 宁振[2] 周涛[1] 蔡欣[1] 刘基巍[1] 

机构地区：[1]大连医科大学附属第一医院肿瘤科,辽宁大连116000 [2]大连医科大学附属第一医院肝胆外科,辽宁大连116000

出　　处：《现代肿瘤医学》2014年第2期379-383,共5页Journal of Modern Oncology

摘　　要：目的:探讨晚期不可手术的IV期恶性肿瘤患者合并恶性肠梗阻(MBO)的预后因素。方法:选取70例随访资料完整的合并MBO的晚期肿瘤患者,并记录患者的人口统计学、临床特点、实验室检查、影像学检查及ECOG评分等特征。随访结束至2012年12月。单因素生存分析采用Kaplan-Meier生存曲线,多因素分析采用COX比例风险回归模型。结果:是否伴有腹膜转移和腹水、梗阻部位、ECOG评分、白蛋白水平、MBO诊断后治疗模式(后续治疗vs支持治疗)均可影响MBO患者的预后,但仅ECOG评分、MBO诊断后治疗模式可作为影响MBO患者预后的独立危险因素。结论:MBO受各种因素影响。Objective：To investigate the prognostic factors in patients with non - curative stage IV cancer and malignant bowel obstruction（ MB0）. Methods ： All 70 cases of MBO patients with colnplete follow - up data were collected into the study. Demographic,clinical,laboratory,radiographic information and the patient＇s functional status （Eastern Cooperative Oncology Group score, ECOG） were recorded. Follow - up was until death or the end of the study （December 2012）. Survival was estimated using Kaplan - Meier plots and COX regression models were used to evaluate prognostic factors for s revival. Results ： Carcinomatosis, ascites, ECOG performance status, obstructive site, albumin level,and post - incident treatment model were correlated to the prognosis of MBO,but only ECOG performance status and post -incident treatment model were the independent prognostic indicators. Conclusion：MBO is influenced by meltifactors.

关 键 词：恶性肠梗阻 生存期 预后因素 

分 类 号：R730.6[医药卫生—肿瘤] R730.7[医药卫生—临床医学]