尼莫地平在动脉瘤夹闭术术中灌洗的疗效  

Clinical outcomes of nimodipine injection used in neurosurgical clipping of intracranial aneurysms

作　　者：唐金沙[1] 冯春国[1] 王晓健[1] 

机构地区：[1]安徽医科大学第一附属医院神经外科,合肥230022

出　　处：《安徽医学》2014年第1期57-59,共3页Anhui Medical Journal

摘　　要：目的探讨尼莫地平在颅内动脉瘤夹闭术术中灌洗的临床疗效。方法回顾性分析60例入院时Hunt-Hess分级在I-III级并行开颅手术治疗的颅内动脉瘤患者的临床资料,其中灌洗组(术中应用尼莫地平灌洗)30例,对照组(术中未应用尼莫地平灌洗)30例,对两组术后第1天CT影像改变和出院时预后(改良Rankin评分表)进行比较分析。结果灌洗组和对照组术后第1天梗死率和出院时预后平均评分差异均无统计学意义(P>0.05)。结论尼莫地平在颅内动脉瘤夹闭术术中灌洗无临床价值。Objective To study the clinical outcomes of nimodipine injection used in the neurosurgical clipping of intracranial an- eurysms. Methods We enrolled 60 patients whose Hunt-Hess classification was in one to three level and who had intracranial aneurysm clipped by surgical operation. They weer equally assigned to lavage group （ nimodipine was used in operation ） and control group （ nimodipine was not used in operation）. Hospitalization days, postoperative CT changes on the first day and discharge prognosis （assessed by modified Rankin scale） of the two groups were analyzed. Results There was no statistically significant difference in the postoperative infarction rate and postoperative outcomes of lavage group and control group （ P 〉 0.05 ）. Conclusion Nimodipine injection used in the neurosurgical clip- ping intracranial aneurysms has no clinical value.

关 键 词：尼莫地平 颅内动脉瘤 灌洗 

分 类 号：R739.4[医药卫生—肿瘤]