生长抑素和生长激素在肠外瘘保守治疗中的临床应用  

Somatostatin and growth hormone in management of gastrointestinal fistulas

作　　者：林希[1] 周喜洋[1] 

机构地区：[1]浙江省天台县人民医院普外科,浙江天台317200

出　　处：《中国现代医生》2014年第3期43-45,共3页China Modern Doctor

基　　金：浙江省台州市科技计划项目(100KY58)

摘　　要：目的 观察生长抑素和生长激素在肠外瘘治疗中的疗效.方法回顾性分析2004 年1 月-2012 年12 月期间收治的各类肠外瘘患者68 例,其中31 例患者给予了生长抑素治疗,37 例患者给予了生长抑素与生长激素联合疗法.观察两组间的临床治疗效果.结果 相比于单纯生长抑素治疗组,生长抑素联合生长激素治疗组患者自愈率提高（89.18% VS 67.74%,P〈0.05）,平均瘘口闭合时间缩短[（22.58±7.83）d vs （28.35±10.56）d;P〈0.05],平均住院时间缩短[（43.89±7.43）d vs （52.61±6.54）d],两组均无严重治疗相关并发症发生.结论联合应用生长抑素与生长激素对治疗肠外瘘有良好的效果,值得临床推广应用.Objective To investigate the role of somatostatin and growth hormone in the management of gastrointestinal fistulas. Methods There were 68 cases of gastrointestinal fistulas in our hospital from Jan 2004 to Dec 2012. Among them, thirty-one patients were received somatostatin only （group A）, while the other received somatostatin and growth hormone sequentially （group B）. The clinical data were analyzed retrospectively. Results Compared with the group A, the curing rate of the group B was increased （89.18% vs 67.74%, P〈0.05）, as well as average fistulas closed time and hospitalization time shortened （22.58±7.83）d vs （28.35±10.56）d;P〈0.05, （43.89±7.43）d vs （52.61±6.54）d, respectively. No serious complications occurred in the two groups. Conclusion Somatostatin combined with growth hormone can significantly improve the clinical treatment effect of gastrointestinal fisfula, it＇s worth clinical application.

关 键 词：肠外瘘 生长抑素 生长激素 

分 类 号：R574[医药卫生—消化系统]