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作 者:师颖瑞[1,2] 刘珈 杨锫[1,2] 谢冠慧 席许平[1,2] 王晖
机构地区:[1]湖南省肿瘤医院 [2]中南大学湘雅医学院附属肿瘤医院放疗科,湖南长沙410013
出 处:《现代生物医学进展》2014年第1期132-135,155,共5页Progress in Modern Biomedicine
摘 要:目的:探索磁感应热疗技术联合放疗治疗不宜手术的颈部淋巴结复发的疗效和安全性。方法:2012年2月至2012年7月选取27例不宜手术的颈部淋巴结复发病例,给予2次磁热籽植入和4-8次不等的加热治疗,计划治疗目标温度为48-50℃、维持30min,磁感应治疗后一周内行放射治疗,治疗结束后1-3个月时复查CT,治疗后6月内不予化疗。结果:治疗结束后3个月时,27例患者中CR55.6%,PR37%,NC3.7%,PD3.7%,治疗总有效率为92.6%;25例疼痛缓解,疼痛缓解有效率92.6%。治疗结束后6个月未发现远处转移病例,未发生大出血、放射性食管炎、放射性骨坏死、骨髓抑制、粒子移位脱落等并发症。结论:磁感应热疗联合放疗治疗不宜手术的复发颈部淋巴结安全、有效。Objective: To investigate the efficiency and safety of magnetic induction therapy combined with radiotherapy for recurrent cervical tumors located. Methods: From February 2012 to July 2012, we chose 27 patients of the inoperable recurmet cervical lympho nodes. We heated the tumors after the implantation immediately. 4-8times were carried out for each tumor, the aimed temperature was 48-50℃, and preserving 30mins each time. Treatment of magnetic induction therapy within one week after the radiation therapy, and CT was rechecked after the treatment in 1-3 months, not receiving chemotherapy within 6 months. Results: In the third month after the teatment, The CR ,PR, NC, PD was 55.6%, 37%, 3.7%, 3.7% respectively were observed in the 27 patients. None of the patients developed distant metastases,and none of the patients occured massive haemorrhage, radiation esophagitis, osteoradionecrosis, bone marrow depression or abscission of the seeds, in 6 months. Conclusion: The magnetic induction therapy combined with radiotherapy for recurrent cervical lymph nodes is a effective and safe treatment with less toxicity.
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