失代偿期肝硬化患者感染的危险因素及临床特点分析  

Analysis of the Risk Factors and Clinical Features for the Infections of Cirrhosis Patients at Decompensated Period

作　　者：熊愫兵[1] 李中艳[2] 付静[3] 柴进[3] 张婷[3] 房殿春[3] 

机构地区：[1]枝江市人民医院消化内科,湖北枝江443200 [2]宜昌市中心人民医院消化内科,湖北宜昌443000 [3]第三军医大学西南医院消化内科,重庆400038

出　　处：《现代生物医学进展》2013年第36期7104-7107,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81070320)

摘　　要：目的:分析失代偿期肝硬化患者感染的相关危险因素和临床特点。方法:回顾性分析我院2012年4月-2013年4月住院的197例肝硬化失代偿期患者,比较感染患者与非感染患者的年龄、性别、肝功能分级、白细胞水平、门静脉内径、肝硬化并发症、侵入性操作措施、应用抗菌药物、住院时间等差异。结果:197例患者中发生感染的56例,其中以呼吸道和腹部感染为主。统计发现肝功能分级、白细胞水平、侵入性操作、住院时间及抗菌药的运用等与感染因素有关(P<0.05)。结论:引起失代偿期肝硬化感染的危险因素是多方面的,临床特点也较突出,需要我们采取防措施去避免。Objective： To analyze the risk factors and clinical features of patients with decompensated liver cirrhosis infection. Methods： A retrospective analysis about 197 cases with liver cirrhosis who were treated in our hospital from April 2012 to April 2013 were selected. Then the age, gender, liver function, white blood cell, portal vein diameter, complications of liver cirrhosis, penetration of operating measures, antibiotics and hospitalization were compared between infected patients and non-infected patients. Results： 56 pa- tients with infection had mainly respiratory tract and abdominal infection from 197cases. It is found that the grade of liver function, white blood cell level, invasive operation, hospitalization time and antibacterial drug had the relationship with infection factors （P〈0.05）. Conclusion： The risk factors of cirrhosis infection are in many aspects, clinical features is outstanding, we need to take preventive mea- sures to avoid.

关 键 词：肝硬化失代偿期 感染 危险因素 临床特点 

分 类 号：R575.2[医药卫生—消化系统]