单壁碳纳米管在癌症激光热疗中的热分析  

Thermal analysis of Single-Wall Carbon Nanotubes in laser hyperthermia of cancer

作　　者：张红艳[1] 白长青[2] 杜建科[3] 

机构地区：[1]长安大学,西安710064 [2]西安交通大学,西安710049 [3]宁波大学,宁波315211

出　　处：《应用力学学报》2014年第1期122-125,11,共4页Chinese Journal of Applied Mechanics

基　　金：国家自然科学基金(11002106);中央高校基本科研业务专项基金(CHD2009JC074);浙江省重中之重"近海冲击与安全"项目开放课题资助(zj1112)

摘　　要：为了研究单壁碳纳米管(SWNTs)在癌症热疗中的应用,本文采用ANSYS软件并进行二次开发,建立了表面随机分布SWNTs的癌细胞生物组织的三维有限元模型;对该模型进行了激光作用下的热分析,并将结果与已有的多壁碳纳米管(MWNTs)相关实验进行了对比;通过数值算例研究了SWNTs的数量、形态参数、激光强度等因素对其瞬态温度场的影响。结果表明:溶液温度随MWNTs数量和时间的增加而增加,且两者的变化趋势是一致的;细胞的中心瞬时温度随SWNTs的数量、长度、半径、激光强度的增加而增加,且均表现为线性增长。Laser hyperthermia of cancer using single-wall carbon nanotubes(SWNTs) is of great interest to researchers due to its highly activity and selectivity. In this paper, a three dimensional finite element model of tissue box including random distributed SWNTs and cancer cell is developed. Thermal analysis of the model subjected to laser radiation is conducted with secondary development of software ANSYS. Both of our numerical results and published experimental data of Multi-wall carbon nanotubes(MWNTs) show similar changing trend,that is, MWNTs solution temperature increases with the number of MWNTs and time. The influences of the number and parameters of morphology of SWNTs as well as laser intensity on the transient temperature distribution are numerically investigated. The numerical results show that the transient temperature at center of the cell rises linearly with the increasing of the number, length and radius of SWNTs as well as the laser intensity.

关 键 词：单壁碳纳米管 癌症 热分析 有限元方法 

分 类 号：R730.5[医药卫生—肿瘤]