阿尔茨海默病侧脑室角度变化的高场磁共振研究  

Study of high magnetic resonance imaging on the angle variation of the lateral ventricles in patients with Alzheimer disease

作　　者：石俊[1] 李月峰[1] 李燕[1] 许萍[1] 邵文杰[1] 

机构地区：[1]江苏大学附属医院影像科,江苏镇江212013

出　　处：《现代医药卫生》2014年第4期495-496,共2页Journal of Modern Medicine & Health

基　　金：镇江市科技计划项目(SH2013025);江苏大学临床医学科技发展基金资助(JLY2010152)

摘　　要：目的探讨阿尔茨海默病(AD)患者侧脑室角度的变化情况。方法对2010年12月至2012年3月20例AD患者(AD组)及20例健康志愿者(对照组)行全脑磁共振成像扫描,对比分析其侧脑室角度的变化规律。结果 AD组双侧侧脑室前后角均较对照组增大,差异有统计学意义(P<0.05);双侧颞角宽度明显较对照组增大,差异有统计学意义(P<0.001)。结论侧脑室角度的变化可为AD的临床诊断提供可信的影像学依据,借助此思路可有助于AD的诊断。Objective To investigate the change of lateral ventricle angle variation of patients with Alzheimer disease （AD）. Methods 20 patients with AD（AD group） and 20 healthy volunteers（control group） from December 2010 to March 2012 were both subject to craniocerebral magnetic resonance imaging （MR!） scanning and their lateral ventricles were compared and analyzed. Results The anterior horn and posteior horn of literal ventricles in AD group were bigger than those in the control group with statistically significant difference （P〈0.05）. The temporal horn of the lateral ventricles in AD group increased more obvi- ously than that in the control group with statistically significant difference （P〈0.001）. Conclusion The change of angle variation of lateral ventricle provides imaging basis for the clinical diagnosis of AD, which will be conducive to the diagnosis of AD.

关 键 词：阿尔茨海默病 侧脑室 磁共振成像 

分 类 号：R749.16[医药卫生—神经病学与精神病学]