秀丽莓茎中酚类成分研究(英文)  

Phenolic Compounds from Stems of Rubus amabilis Focke

作　　者：刁玉林[1] 热增才旦[1,2] 王如峰[1] 刘斌[1] 

机构地区：[1]北京中医药大学中药学院,北京100102 [2]青海大学医学院中藏药研究中心,西宁810001

出　　处：《天然产物研究与开发》2014年第1期11-14,49,共5页Natural Product Research and Development

基　　金：financially supported by the National Natural Science Foundation Project(No.81260684);the Research Fund for self-selected Topic of Beijing University of Chinese Medicine(No.2013-jybzz-xs-113)

摘　　要：秀丽莓（RubusamabilisFoeke）为蔷薇科悬钩子属植物，系常用藏药，已有1300多年历史。本实验从其茎中分离了8个化合物，通过波谱法和理化性质分别鉴定为：4-乙酰氧5-3-甲氧基苯甲酸（1）、2-O-β-D-吡喃葡萄糖基-6．羟基苯甲酸（2）、香草酸（3）、白藜芦醇（4）、2，6-二甲氧基-4．羟苯基-1-O-β-D-吡喃葡萄糖苷（5）、反式-4-羟基桂皮酸（6）、咖啡酸（7）及没食子酸（8）。其中1为新天然产物，化合物2-7均为首次从该植物中分离得到。The constituents of Rubus amabilis were isolated and purified by silica gel column chromatography, Sephadex LH-20, macroporous adsorption resin and TLC. The structures of the purified compounds were elucidated on the basis of spectral data and physiochemical properties. Eight compounds were isolated and their structures were identified as：4- acetoxy-3-methoxybenzoic acid （ 1 ）, 2- （β-D-glucopyranosyloxy） -6-hydroxybenzoic acid （2）, vanillic acid （ 3 ）, resvera- trol （ 4 ）, 2,6-dimethoxy-4-hydrexyphenol-1-O-β-D-glucopyranoside （ 5 ）, trans-4-hydrexy cinnamic acid （ 6 ）, caffeic acid （7） and gallic acid （8）. Compound I was a new natural product. Compounds 2-7 were isolated from Rubus amabilis for the first time.

关 键 词：秀丽莓 悬钩子属 酚类 结构解析 

分 类 号：R932[医药卫生—生药学]