大鼠脑胶质瘤模型的MRI表现  

MRI presentation of rat brain-glioma model

作　　者：吴国祥[1] 余绍祖[1] 李承晏[1] 李涛[1] 牛琦[1] 喻文莉[1] 李茂进[2] 

机构地区：[1]湖北医科大学附属第一医院神经科,武汉430060 [2]湖北医科大学附属第一医院磁共振室,武汉430060

出　　处：《卒中与神经疾病》2001年第1期32-34,共3页Stroke and Nervous Diseases

摘　　要：目的　研究大鼠脑胶质瘤模型的MRI表现。方法　经病理和免疫组织化学染色证实的大鼠脑胶质瘤 2 0例 ,分析其MRI表现。结果　大鼠脑胶质瘤在T1WI上呈等信号。T2 WI上呈高信号 ,边界较清楚。术后第 16天时 10只大鼠出现较轻的占位效应 ,术后第 2 5天时 2 0只大鼠均出现明显的占位效应。增强扫描 :2 0只大鼠出现肿瘤呈环状强化。结论　 0 5TMR -T2 WI和结合用Gd -DTPA行增强扫描能清楚显示大鼠脑胶质瘤。Objective To investigate MRI presentation of rat brain-glioma model.Methods The MRI findings of 20 rats with brain-glioma was analyzed.The diagnosis was confirmed by pathology and immunohistochemistry.Results The rat brain-glioma showed iso-signal intensity on T 1WI and hyperintensity with well defined margin on T 2WI mild and marked mass effect are noted in 10 rats and 20 rats at the 16 th and 25 th day respectively after implantation. There was a circle enhancement in 20 rats with contrast enhoncement.Conclusion The rat brain-glioma could be best detected on MR-T 2WI and with contrast enhancement.

关 键 词：C6胶质瘤 MRI 免疫组织化学 脑胶质瘤 

分 类 号：R739.41[医药卫生—肿瘤]