幽门螺杆菌基因分型的研究进展  

Research Progress on Genotyping of Helicobacter Pylori

作　　者：苏敏[1] 张丽颖[2] 王凤云[2] 李振华[2] 李保双[2] 唐旭东[2] 

机构地区：[1]中国中医科学院研究生院,北京100070 [2]中国中医科学院西苑医院,北京100091

出　　处：《辽宁中医杂志》2014年第2期369-372,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局中医药行业科研专项资助项目(201007006)

摘　　要：幽门螺杆菌(Hp)为胃炎、消化性溃疡的病因,基因分型是触及生命本质的方法,不同基因分型与疾病相关性不同、其耐药性也不同。文章从Hp基因分型入手,通过以下四个方面:不同基因分型与疾病的相关性、不同基因分型的耐药情况、不同基因分型与黏膜损害程度的关系以及中医药抗Hp的干预环节,简要总结了近7年幽门螺杆菌基因分型的研究情况,为中医药抗Hp治疗提供新方法,发现新药物。Helicobacter pylori （Hp） infection can cause gastritis and peptic ulcer. The genotyping can show the essence of life. Different genotyping is correlated with different diseases and different genotyping correlated with different resistances. This ar- ticle observed the I-Ip genotyping. There were four aspects to discuss：The correlation on different genotyping with the disease;dif- ferent genotyping resistant;the different genotyping mucosal damage intensity;intervention link of traditional Chinese medicine. A brief summary of the nearly seven years of Hp genotyping research provides a new method to discover new drugs for the treatment of Hp with traditional Chinese medicine.

关 键 词：幽门螺杆菌 基因分型 研究进展 

分 类 号：R573.3[医药卫生—消化系统]