介入化疗治疗复发子宫颈癌  

Interventional Chemotherapy for Recurrent Cervical Carcinoma

作　　者：林厚斌[1] 赵玉年[1] 何丹[1] 郑满荣[2] 

机构地区：[1]江苏省肿瘤医院,江苏南京210009 [2]海军安庆医院,安徽安庆246000

出　　处：《河南肿瘤学杂志》2001年第1期17-18,共2页Henan Journal of Oncology

摘　　要：目的　探索复发宫颈癌的治疗方法。方法　从 1996年 6月至 1998年 6月对 2 1例复发性宫颈癌行介入化疗 ,其中术后复发 3例。放疗后复发 15例 ,手术及放疗后复发 3例。灌注的药物PDD 10 0～ 15 0mg ,5 -Fu 1 0～ 1 5g ,MMC 10～ 14mg加超液化碘 5ml。栓塞有 8例 ,患者配合放疗。结果　CR 5例 ,PR 6例 ,总有效率为 5 2 3 8% ,中位生存时间为 13 5个月。结论　复发性宫颈癌采用超选择动脉介入化疗是一种有效、安全的治疗方法。Objective To approach the means of treating patinets with recurrent cervical carcinoma.Methods 21 patinets with recurrent cervical carcinoma were treated from June 1996 to June 1998 by super selective internal artery catherization chemotherapy. There were 3 recarrent patients after surgery, 15 after radiotherapy and 3 after radiotherapy and surgry. The treatment consisted of super selective artery infusion of 5-Fu 1.0～1 5 g, PDD 100～150 mg, MMC 10～14 mg and strong liquefied iodine 5 ml embolication. There were 8 patients with embolism receiveing concurrent radiottherapy.Results The response rate(CR+PR) was 52.38% and the median survival time was 13.5 months. the Toxicity due to chemotherapy was usually mild and reversible.Conclusions Interventional chemotherapy can improve immediate effect for recurrent cervical carcinoma.

关 键 词：介入化疗 宫颈癌 复发 治疗 

分 类 号：R737.330.5[医药卫生—肿瘤]