金陵术治疗成人先天性巨结肠远期疗效及生活质量分析  

Long term outcomes and quality of life after Jinling procedure for adult Hirschsprung's disease

作　　者：王林[1] 姜军[1] 丁威威[1] 李宁[1] 

机构地区：[1]南京大学医学院南京军区南京总医院解放军普通外科研究所,江苏南京210002

出　　处：《中国实用外科杂志》2014年第2期164-166,共3页Chinese Journal of Practical Surgery

基　　金：南京军区医学科技创新课题面上项目(12MA081);江苏省临床医学科技专项(BL2012006)

摘　　要：目的评价金陵术治疗成人先天性巨结肠的安全性、有效性和对病人生活质量的影响。方法对2008年6月至2011年12月南京军区南京总医院行金陵术治疗的25例先天性巨结肠便秘病人临床资料进行回顾性分析。结果术后平均随访(3.0±1.1)年,至2013年6月仍保持随访。手术均成功。无手术相关死亡病例。术后并发症:腹泻、肛门疼痛、吻合口瘘、小肠梗阻和术后尿潴留,其中大部分可通过保守治疗缓解。病人的便秘症状评分和肠道功能评分在术后均有明显改善(P<0.01),胃肠道生活质量评分明显提高(P<0.01)。病人均满意。结论金陵术治疗成人先天性巨结肠安全、有效,病人术后生活质量恢复良好。Objective To evaluate the safety, effectiveness and quality of life of Jinling procedure for adult Hirschsprung＇ s disease. Methods The clinical data of 25 cases performed Jinling procedure for adult Hirschsprung＇ s disease between June 2008 and December 2011 in Nanjing General Hospital of Nanjing Military Command were analyzed retrospectively. Results The mean postoperative period followed up had been （3.0±1.1） years until June 2013. All the operations were successful. No surgical related death was reported. Adverse events mainly included diarrhea, anus pain, anastomotic leakage, small intestinal obstruction and postoperative urinary retention. Most of the complications could be managed conservatively. A significant improvement in Wexner constipation scale, bowel function score and gastrointestinal quality of life index was obtained after Jinling procedure （P〈0.01）. All the patients were satisfied with the outcomes. Conclusion Jinling procedure is safe and effective for adult Hirschsprung＇ s disease and patients＇ quality of life index after Jinling procedure is very high after long term follow-up.

关 键 词：成人先天性巨结肠 生活质量 金陵术 远期疗效 

分 类 号：R6[医药卫生—外科学]