Ⅵ区淋巴结转移状态预测颈部淋巴结阴性甲状腺乳头状癌侧颈转移的可行性探索  

The feasibility of Ⅵ region lymph nodes metastasis status in prediction of lateral lymph nodes metastasis in papillary thyroid carcinoma with negative cervical lymph nodes

作　　者：刘木元[1] 郭海鹏[1] 彭汉伟[1] 杨熙鸿[1] 

机构地区：[1]汕头大学医学院附属肿瘤医院头颈科,广东汕头515000

出　　处：《中国医师进修杂志》2014年第2期1-3,共3页Chinese Journal of Postgraduates of Medicine

基　　金：广东省自然科学基金（s2011010005042）;广东省科学计划项目（20101096）;广东省汕头市科学技术计划项目（2010480）;汕头大学医学院附属肿瘤医院青年基金（2011A003）

摘　　要：目的 探讨利用Ⅵ区淋巴结转移状态预测颈部淋巴结阴性（cN0期）甲状腺乳头状癌侧颈淋巴结转移的可行性.方法 回顾性分析2003年1月至201 1年10月接受同侧预防性颈部淋巴结清扫（Ⅱ～Ⅴ区或Ⅱ～Ⅳ区）的73例cN0期甲状腺乳头状癌患者的临床资料,分析Ⅵ区淋巴结转移与侧颈淋巴结转移的相关性.结果 73例cN0期甲状腺乳头状癌患者中,侧颈淋巴结转移率为16.4％（12n3）,Ⅵ区淋巴结转移率为42.5％（31/73）,多因素分析显示Ⅵ区淋巴结转移是影响cN0期甲状腺乳头状癌侧颈淋巴结转移的独立危险因素（OR=7.3,P=0.020）.结论 Ⅵ区淋巴结转移状态用于预测cN0期甲状腺乳头状癌侧颈淋巴结转移是可行的.Objective To evaluate if Ⅵ region lymph nodes metastasis status can be a reliable indicator in prediction of lateral lymph nodes metastasis in papillary thyroid carcinoma （PTC） with negative cervical lymph nodes （cN0）.Methods Retrospectively reviewed the medical records from January 2003 to October 2011 of 73 patients with PTC who underwent prophylactic lateral neck dissection （Ⅱ-Ⅴ region or Ⅱ-Ⅳ region）.The relationship between cervical lymph nodes metastasis and lateral lymph nodes metastasis was assessed.Results The rate of lateral lymph nodes metastasis was 16.4％（12/73）.The rate of Ⅵ region lymph nodes metastasis was 42.5％（31/73）.Multivariate analysis showed that Ⅵ region lymph nodes metastasis was the risk factor of lateral lymph nodes metastasis in cN0 patients with PTC（OR =7.3,P=0.020）.Conclusion Ⅵ region lymph nodes metastasis status can be a reliable indicator of lateral lymph nodes metastasis in cN0 patients with PTC.

关 键 词：甲状腺肿瘤 淋巴转移 颈淋巴结清扫术 

分 类 号：R736.1[医药卫生—肿瘤]