幽门螺杆菌不是慢性胃病的主要致病因素——附378例临床调查报告  被引量:1

Helicobacter pylori is not the main pathogenesis of chronic gastropathy according to 378 cases report

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作  者:罗珠林[1] 陈渝[2] 刘炼炼[2] 杨娜[2] 王玲[2] 

机构地区:[1]成都军区总医院消化内科,四川成都610083 [2]成都军区总医院消化内镜中心,四川成都610083

出  处:《中国中西医结合消化杂志》2014年第1期30-32,35,共4页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘  要:[目的]验证幽门螺杆菌(Hp)是否为慢性胃病的主要致病因素。[方法]用概率、构成比、相对比对378例慢性胃病患者进行统计分析。[结果]慢性活动性胃炎213例,Hp阳性概率为0.253 5,Hp阳性例数构成比为25.35%;Hp阴性概率为0.746 5,Hp阴性例数构成比为74.65%,Hp阴性例数与Hp阳性例数的相对比为2.94(倍)。溃疡病(A1期)165例,Hp阳性概率为0.406 1,Hp阳性例数构成比为40.61%;Hp阴性概率为0.593 9,Hp阴性例数构成比为59.39%,Hp阴性例数与Hp阳性例数的相对比为1.46(倍)。[结论]Hp不是胃炎及溃疡病的主要致病因素,Hp可能对胃黏膜屏障起保护作用。[Objective]To verificate whether the Helicobacter pylori (Hp) is the main pathogenic factor of chronic gastropathy, l-Methods]Three hundred and seventy-eight patients with chronic gastropathy were analyzed with probability, the constituent ratio of chronic gastropathy and relative ratio, l-Results]In 213 ca- ses of chronic active gastritis, Hp positive probability was 0. 253 5, Hp positive cases ratio was 25.35%, Hp negative probability was 0. 746 5,the ratio was 74.65%. The ratio of Hp negative cases to Hp positive cases was 2.94. In 165 cases of peptic ulcer (A1), Hp positive probability was 0. 4061, Hp positive cases ratio was 40. 61%, and Hp negative probability was 0. 5939,the ratio was 59.39%. The ratio of Hp nega- tive cases to Hp positive cases was 1.46. [Conclusion]Hp is not the main pathogenic factor of gastritis and ulcer disease. And it may have protective effect on the gastric mucosal barrier.

关 键 词:幽门螺杆菌 慢性胃炎 溃疡病 致病因素 

分 类 号:R573.3[医药卫生—消化系统]

 

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