CT引导下^(125)I粒子植入治疗肺癌的并发症及临床处理  

Complications of CT-guided ^(125)I particle implantation for lung cancer treatment

作　　者：谢小西[1] 吕银祥[1] 季勇[1] 王晓伟[1] 章国东[1] 杨利萍[1] 

机构地区：[1]新昌县人民医院介入中心,浙江312500

出　　处：《影像诊断与介入放射学》2013年第6期439-442,共4页Diagnostic Imaging & Interventional Radiology

摘　　要：目的分析CT引导下^(125)I粒子植入治疗肺癌的并发症并探讨临床处理。方法 58例肺癌患者,年龄37~85岁,肿瘤大小1.5~7 cm,全部患者在CT引导下进行肺部肿瘤^(125)I粒子植入治疗,1~3次/人,植入粒子8~51颗/次。结果本组共进行粒子植入73人次,粒子植入治疗过程中发生气胸、针道渗血、咯血和胸腔出血25人次(34.2%),多种并发症可以同时发生,通过止血治疗、胸腔引流等处理均好转,未发生大咯血、死亡等严重并发症;2例患者(3.45%)出现肿瘤针道种植,其中1例对针道种植肿瘤行^(125)I粒子治疗。结论 CT引导下^(125)I粒子植入治疗肺癌,常见并发症为气胸、咯血和胸腔出血,少数病例发生肿瘤针道种植,需要及时有效处理。Objective To assess the complications of CT-guided percutaneous 125I particle implantation for treatment of lung cancer. Methods 58 patients （ age range： 37-85 years） with lung cancer mass were treated with CT-guided percutaneous 125I particle implantation. The tumor masses measured 1.5-7 cm in diameter. Each patient was treated 1-3 times with 8-51 125I particles in each treatment. Results Of a total of 73 treatments, complication rate was 25 （34.2%） including pneumothorax, bleeding along the needle tracts, hemoptysis and hemothorax. The complications may occur simultaneously in the same patient. All complications were controlled with conservative hemostatie treatment or drainage. There was no death. Tumor seeding along the needle tracts was found in 2 patients （3.5%）, one of whom was treated with repeat 125I particle implantation along the needle tracts. Conclusions The complications of CT- guided percutaneous 125I particle implantation included pneumothorax, hemoptysis and hemothorax. Tumor seeding along the needle tracts was infrequent. All complications can be treated effectively.

关 键 词：肺肿瘤 CT引导 ^125I粒子 并发症 内照射治疗 

分 类 号：R734.2[医药卫生—肿瘤]