T2-SPACE序列MRI正常人脑池段眼球运动神经的成像  

T2-SPACE MRI for the ocular motor nerves in the brainstem of normal controls

作　　者：李瑞利[1] 夏爽[1] 王健[1] 祁吉[1] 

机构地区：[1]天津市第一中心医院放射科,300192

出　　处：《中华医学杂志》2014年第3期163-166,共4页National Medical Journal of China

摘　　要：目的采用MRI技术研究正常人眼球运动有关的颅神经（即眼球运动神经）脑池段的影像特征。方法收集2008年12月至2009年12月天津市第一中心医院放射科健康受试者68名，颅内神经行3DT2-SPACE序列扫描，扫描参数为TR=1000ms，TE=134ms，采集2次，层厚0．8mm，FOV=225mm×225mm，矩阵=384×384，扫描时间为4min2s。运用多平面重组技术进行多维重组，分别在沿神经长轴的层面显示3对眼球运动神经的走行和毗邻结构。2位放射科医师于脑池段独立测量动眼神经、展神经的直径。结果68名志愿者，136侧动眼神经和外展神经脑池段100％显示，滑车神经87％显示；脑池段动眼神经、展神经直径平均分别为2．2、1．3mm，2位医师测量结果差异无统计学意义（F=2．557，1．329；P=0．085，0．271），本组受试者动眼神经、展神经直径与年龄没有线性相关。结论连续的薄层三维T2-SPACE序列扫描结合多平面重组技术可以清晰显示眼运动神经脑池段及其毗邻关系。确切的影像数据测量为某些特殊性的神经源性斜视提供更准确的解剖依据。Objective To study the detail functional anatomy of ocular motor nerves in the brainstem by high-resolution magnetic resonance imaging （ MRI）. Methods Sixty eight normal subjects with high resolution MRI were recruited in our study. The ocular motor nerves at the brainstem were performed using 3-dimensional, TE-weighted Turbo-Spin-Echo sequence with high sampling efficiency sequence （3D T2-SPACE） ,Parameters： TR = 1000 ms, TE = 134 ms, averages = 2, thickness =0. 8 mm, FOV = 225 mm × 225 mm, matrix = 384 ×384, total scanning time is 4 min 2 s. Nerves in the brainstem were observed in oblique axial, oblique sagittal and coronal planes acquired with multi-planar reformation （MPR）. The diameters of oculomotor nerves （CN3） and abducens （CN6） in the brainstem were measured in 68 normal subjects on MR images by 2 neuro-radiologists. Results All of 136 CN3 and CN6 of the cisternal segment were well demonstrable in 68 normal subjects （ 100% ）. Trochlear nerves （ CN4 ） were depicted 87%. The diameters of CN3 and CN6 in the cistern were 2. 2 mm, 1.3 mm, had no linear correlation with age. There were no significant difference between the results of the 2 radiologist （ F = 2. 557, 1. 329, P = 0. 085, 0. 271 ）. Conclusions T2-SPACE sequence combined with MPR could precisely show the ocular motor nerves, as well as the relationship with adjacent structures in the cistern. The exact data measurement can provide more accurate anatomical basis for some special forms of neuropathic strabismus.

关 键 词：磁共振成像 眼神经 T2-SPACE序列 

分 类 号：R777.41[医药卫生—眼科] R445.2[医药卫生—临床医学]