壳聚糖复合膜剂的制备及性能研究  

Preparation and characteristics of composite chitosan membranes

作　　者：关丽[1] 黄国程 杨宝芸[1] 陈琳[1] 王秀珍[1] 

机构地区：[1]广东药学院药科学院,广州510006

出　　处：《海峡药学》2014年第1期25-28,共4页Strait Pharmaceutical Journal

基　　金：广东省科技计划项目;2012B031800228

摘　　要：目的制备物理性能良好的壳聚糖(CTS)复合膜。方法将壳聚糖与明胶、可溶性淀粉、聚乙烯醇等3种不同材料共混成膜,使用甘油或聚乙二醇600(PEG600)为增塑剂,探讨所得膜的保湿性能、吸湿性能和水蒸气透过性能的变化规律。结果含量为20%的增塑剂均能达到较好的保湿性能和水蒸气透过率,且大多数情况下,甘油的增塑效果优于PEG。吸湿性能方面,CTS-淀粉复合膜与其它复合膜有些不同,随增塑剂含量增加,吸湿率有极大值出现。结论壳聚糖与其它水溶性高分子材料复合成膜后,其综合性能均有所提高。OBJECTIVE To prepare composite Chitosan （CTS） membranes with good physical proper- ties. METHODS Composite membranes have been made blending chitosan with glutin, dissolvable starch, or poly- vinyl alcohol （PVA）. The physical properties of composite membranes, such as moisture retention, hygroscopicity and moisture permeability, have been researched, using glycerol or polyethylene glycol （PEG 600 ） as plastici- zer. RESULTS Adding 20% of the plasticizer could achieve better moisture retention and moisture permeability. In most cases,the plasticizing effect of the glycerol was superior to PEG. Hygroscopicity of CTS-starch composite film was different from the other composite films. With the plasticizer content increasing, the hygroscopicity rate reached a maximum value. CONCLUSION The properties of Chitosan composite membranes have been improved.

关 键 词：壳聚糖膜 混合膜 保湿性能 吸湿性能 水蒸气透过性能 

分 类 号：TQ460.4[化学工程—制药化工]