基于磁共振成像的颈动脉粥样硬化相关血流动力学研究进展  

Hemodynamic Research Development of Carotid Atherosclerosis Based on MR Imaging

作　　者：隋滨滨[1,2] 薛蕴菁[3] 高培毅[1,2] 

机构地区：[1]北京首都医科大学附属北京天坛医院放射科,北京100050 [2]北京市神经外科研究所 [3]福建医科大学附属协和医院放射科

出　　处：《中国卒中杂志》2014年第2期158-162,共5页Chinese Journal of Stroke

基　　金：国自然基金(81301193);北京自然科学基金(7122029)及(7133238)

摘　　要：动脉粥样硬化斑块常发生于血流动力学状态复杂的区域,显示局部血流的流体力学特性在动脉粥样硬化病变发生发展中起到重要作用。基于磁共振成像结合图像后处理技术,可对动脉血流动力学状态进行评估。既往研究已经对正常和狭窄颈动脉的血流动力学特征进行了分析;而血流动力学因素与斑块易损性之间的相关性也已经得到证实。包括管壁应力、压力等动脉血流动力学参数的综合作用是斑块发生发展变化中的重要因素。Atheroslerotic lesions tend to be localized at the area with sophisticated lfow status regardless of the underlying risk factors involved, which suggested that hemodynamic factors play an important and predominant role in formation and development of atherosclerosis. Based on magnetic resonance images, combined with post-processing techniques, hemodynamic status can be assessed. Previous studies have analyzed hemodynamics features in normal and stenosed carotids. The association between hemodynamics factors and plaque vulnerability has been proven. Arterial hemodynamics parameters including wall shear stress, pressure are important factors in formation and development of atherosclerotic plaques.

关 键 词：颈动脉 血流动力学 磁共振成像 

分 类 号：R743[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]