经肝动脉化疗栓塞术联合经皮肝穿门静脉大剂量热碘油栓塞治疗肝转移癌  

Hepatic chemoembolization combined with percutaneous trans- hepatic puncture of portal vein plus heated Lipiodol infusion for the treatment of metastatic liver carcinoma

作　　者：独建库[1] 何伟华[1] 邹洋[1] 马小桔[1] 

机构地区：[1]河南洛阳解放军第105医院介入中心,471031

出　　处：《介入放射学杂志》2014年第2期115-117,共3页Journal of Interventional Radiology

基　　金：军队十二五课题(08Z006)

摘　　要：目的探讨采用经肝动脉化疗栓塞术(TACE)联合经皮肝穿门静脉灌注大剂量加热碘油治疗肝转移癌的方法及疗效。方法肝转移癌患者124例,随机分为联合组62例和对照组62例,分别采用TACE联合经门静脉路径灌注大剂量热碘油和常规TACE治疗。结果术后复查CT、MRI,联合组瘤体缩小率明显高于对照组,术后随访6、12、18、24个月,联合组总有效率为61.3%明显优于对照组的38.7%,两组差异有统计学意义(P<0.05)。结论 TACE联合经皮肝穿门静脉灌注大剂量热碘油治疗肝转移癌疗效比常规TACE方法更有效,是治疗肝转移癌安全有效的选择,具有一定的临床应用价值。[Abstract] Objective To discuss the clinical effect and method of transarterial chemoembolization （TACE） combined with percutaneous trans-hepatic puncture of portal vein plus heated Lipiodol infusion in treating metastatic liver carcinoma. Methods A total of 124 patients with liver metastatic carcinoma were randomly divided into combination group （n = 62） and control group （n = 62）. TACE combined with percutaneous trans-hepatic puncture of portal vein plus heated larger dose Lipiodol infusion was carried out in the patients of the combination group, while only conventional TACE was performed in the patients of the control group. The clinical results were analyzed. Results Postoperative CT and MRI examinations showed that the shrinkage rate of the tumor in the combination group was significantly higher than that in the control group. Postoperative check-ups were made at 6, 12, 18 and 24 months. The total effective rate of the combination group was 61.3%, which was obviously higher than that of the control group （38.7%）. The difference between the two groups was statistically significant （P 〈 0.05）. Conclusion For the treatment of metastatic liver carcinoma, TACE combined with percutaneous trans- hepatic puncture of portal vein plus heated larger dose Lipiodol infusion is more effective than conventional TACE. Therefore, this technique should be recommended in clinical practice. （J Intervent Radiol, 2014, 23：115-117）

关 键 词：肝转移癌 门静脉栓塞术 热碘油 TACE术 

分 类 号：R735.7[医药卫生—肿瘤]