鼻咽癌放疗前后腭帆张肌横截面积的改变与放射性中耳炎的相关性  

Relationship between radioactive otitis media and changes in cross section area of tensor veli palatine( TVP)muscle after radiotherapy in patients with nasopharyngeal carcinoma

作　　者：杨建明[1,2] 

机构地区：[1]苏州市吴江区第一人民医院 [2]南通大学附属吴江医院耳鼻咽喉头颈外科,江苏苏州215200

出　　处：《山东大学耳鼻喉眼学报》2014年第1期31-33,共3页Journal of Otolaryngology and Ophthalmology of Shandong University

摘　　要：目的探讨鼻咽癌放疗前后腭帆张肌横截面积的改变与放射性中耳炎的相关性。方法回顾性分析苏州市吴江区第一人民医院2007年1月至2011年1月就诊的36例接受放射性治疗的鼻咽癌患者的临床资料,于放疗前后分别测量所有患者上腭帆张肌及翼内肌的横截面积,比较放疗前后的差异,并分析患者于放疗后发生放射性中耳炎与腭帆张肌受损之间的相关性。结果放疗后共24例(44耳)并发分泌性中耳炎;放疗后STVP、SLTVP、SRTVP、SLTVPM、SRTVPM、SLTVPF、SRTVPF、SM P、SLM P及SRM P与放疗前相比明显下降(P<0.05);腭帆张肌萎缩耳中分泌性中耳炎的发生率明显高于腭帆张肌无萎缩耳者(72.92%vs 37.50%,χ2=8.445,P=0.004)。结论放疗后鼻咽癌患者的腭帆张肌与翼内肌会发生萎缩,而放疗后分泌性中耳炎的发生与腭帆张肌的萎缩可能有一定的相关性。Objective To study the relationship between radioactive otitis media and changes in cross section area of tensor veli palatine （TVP） muscle after radiotherapy in patients with nasopharyngeal carcinoma. Methods Retrospec- tively analyze the clinical data of 36 patients with nasopharyngeal carcinoma who accepted radiotherapy in our hospital from January, 2007 to January, 2011. The cross section area （CSA） of TVP and medial pterygoid （MP） muscle of all the patients were measured before and after radiotherapy, meanwhile the incidence of SOM was surveyed after radiother- apy. Results Twenty-four cases （44 ears） developed post-irradiation SOM after the radiotherapy. S_TVP、S_LTVP、S_RTVP、S_LTVPM、S_RTVPM、S_LTVPP、S_RTVPP、S_MP、SL_MP and SR_Mp of all patients statistically decreased after radiotherapy （P 〈 0. 05）. Ears with TVP atrophy had a high rate of incidence of SOM than ears without TVP atrophy （72.92% vs 37. 50%, X2 = 8.445, P = 0.004）. Conclusion The atrophy occurs to the CSA of TVP and MP of patients with nasopha- ryngeal carcinoma, which may result in post-irradiation SOM.

关 键 词：鼻咽癌 放射性腭帆张肌损伤 放射性中耳炎 

分 类 号：R739[医药卫生—肿瘤]