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机构地区:[1]天津市人民医院,天津300131
出 处:《中国肿瘤》2014年第2期103-108,共6页China Cancer
摘 要:大肠癌是我国常见的恶性肿瘤之一,早期大肠癌的5年生存率可达90%以上,因此大肠癌高危个体的识别和早期诊断显得尤其重要。常用的筛查措施主要包括粪便潜血实验、钡灌肠检查、纤维乙状结肠镜和结肠镜检查等。目前适用于人群筛查的最佳方法尚不确定,分子筛查及其他新的技术有望用于人群大肠癌筛查。对于各种筛查方法,如何进一步提高其特异性和敏感度,同时在效价比和人群依从性等方面上做出改进是目前研究的热点。Colorectal carcinoma is one of the common malignant tumor in China. Five years sur- vival rate of early colorectal carcinoma may reach over 90%.Therefore, identification and early di- agnosis of colorectal carcinoma in high-risk individuals are particularly important, Screening mea- sures used include fecal occult blood test,barium enema examination,fiber sigmoidoscopy and colonoscopy. The best method for suitable for population screening is still uncertain,molecular screening and other new technology is expected to be used in population screening of colorectal carcinoma. For the various methods for screening,the hotspot of the research is how to further improve the specificity and sensitivity,and improved potency ratio and population's compliance.
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